Interleukin-10 in amniotic fluid at midtrimester: immune activation and suppression in relation to fetal growth

KD Heyborne, JA McGregor, G Henry, SS Witkin… - American journal of …, 1994 - Elsevier
OBJECTIVE: Low birth weight remains the leading cause of perinatal morbidity and
mortality, but mechanisms mediating impaired fetal growth are poorly understood. To further …

[HTML][HTML] Midtrimester amniotic fluid concentrations of interleukin-6 and interferon-gamma-inducible protein-10: evidence for heterogeneity of intra-amniotic …

MT Gervasi, R Romero, G Bracalente… - Journal of perinatal …, 2012 - degruyter.com
Introduction: Intra-amniotic inflammation is traditionally defined as an elevation of amniotic
fluid interleukin (IL)-6. Previous case control studies have suggested an association …

Amniotic fluid interleukin-10 concentrations increase through pregnancy and are elevated in patients with preterm labor associated with intrauterine infection

PC Greig, WNP Herbert, BL Robinette… - American journal of …, 1995 - Elsevier
OBJECTIVE: To better understand the role of the antiinflammatory cytokine interleukin-10 in
preterm labor and infection, we evaluated the amniotic fluid interleukin-10 concentrations …

Second-trimester amniotic fluid interleukin-10 concentration predicts preterm delivery

J Apuzzio, Y Chan, A Al-Khan, N Illsley… - The journal of …, 2004 - Taylor & Francis
Objective: Interleukin-6 (IL-6) is an inflammatory cytokine that has been shown to be
elevated in the amniotic fluid of patients with preterm labor. On the other hand, interleukin-10 …

The anti-inflammatory limb of the immune response in preterm labor, intra-amniotic infection/inflammation, and spontaneous parturition at term: a role for interleukin-10

F Gotsch, R Romero, JP Kusanovic, O Erez… - The Journal of …, 2008 - Taylor & Francis
Objective. The anti-inflammatory limb of the immune response is crucial for dampening
inflammation. Spontaneous parturition at term and preterm labor (PTL) are mediated by …

Interleukin-6 levels in amniotic fluid in normal and abnormal pregnancies: preeclampsia, small-for-gestational-age fetus, and premature labor

RM Silver, B Schwinzer, JA McGregor - American journal of obstetrics and …, 1993 - Elsevier
Objective: Our purpose was to determine if abnormal amniotic fluid interleukin-6 levels
correlate with pregnancies complicated by preeclampsia, small-for-gestational-age fetus …

Second-trimester amniotic fluid or maternal serum interleukin-10 levels and small for gestational age neonates

CY Spong, DM Sherer, A Ghidini, CB Jenkins… - Obstetrics & …, 1996 - Elsevier
OBJECTIVE: To evaluate if interleukin-10 levels in either early second-trimester amniotic
fluid (AF) or maternal serum can be utilized as a predictor of the subsequent occurrence of …

Elevated second-trimester amniotic fluid interleukin-6 levels predict preterm delivery

KD Wenstrom, WW Andrews, JC Hauth… - American journal of …, 1998 - Elsevier
OBJECTIVE: Our purpose was to determine whether early second-trimester amniotic fluid
interleukin-6 levels predict delivery before 34 weeks' gestation. STUDY DESIGN: We used …

Inhibition of interleukin‐10 during pregnancy results in neonatal growth retardation

AG Rijhsinghani, K Thompson… - American Journal of …, 1997 - Wiley Online Library
PROBLEM: Interleukin 10 is considered to be important in the survival of the fetus in murine
pregnancies that are known to be at risk for fetal wastage. The function of IL‐10 in a normal …

Amniotic fluid interleukin-6 increase is an indicator of spontaneous preterm birth in white but not black Americans

R Menon, MC Camargo, P Thorsen… - American journal of …, 2008 - Elsevier
OBJECTIVE: This study examined the differences in the inflammatory cytokine interleukin
(IL)-6 and the immunoinhibitory cytokine IL-10 in the amniotic fluid of black and white …