The acute respiratory distress syndrome (ARDS) is a common and vexing problem faced by
critical care providers worldwide. Despite extensive investigation over the past 3 decades …

Background Acute respiratory distress syndrome (ARDS) is a common and disabling
disease with high rates of mortality and morbidity. The role of steroids in treating ARDS …

CHEST| Volume 131| Number 4| April 2007 www. chestjournal. org CHEST/131/4/APRIL,
2007 945 septic shock that included patients with ARDS and showed significant …

Glucocorticoids (GC) in all its various forms and formulations are likely one of the most
commonly used pharmacologic agents in medicine. Their use can be profoundly therapeutic …

Objectives To compare the design and results of randomized trials investigating prolonged
glucocorticoid treatment (≥ 7 days) in patients with acute lung injury–acute respiratory …

Previous clinical trials have investigated the effect of glucocorticoid therapy in acute
respiratory distress syndrome (ARDS), with controversial results, particularly with regard to …

Objective: Controversy remains as to whether low-dose corticosteroids can reduce the
mortality and morbidity of acute lung injury (ALI) or the acute respiratory distress syndrome …

Objectives To describe hypothalamic-pituitary-adrenal (HPA) activation and the role of
glucocorticoids in immune modulation during critical illness, and to review clinical trials of …

The aim of this study was to describe the role of glucocorticoids in immune modulation
during critical illness and to review clinical trials and recent meta-analyses of glucocorticoids …

The randomized study conducted by Dr. Bollaert and colleagues [1] apparently contradicts
previous large, randomized, multicenter trials investigating sepsis and early acute …