Neurotrophins are a family of soluble ligands that promote the survival and differentiation of
peripheral and central neurons and regulate synaptic function. The two neurotrophins, brain …

In the central nervous system, most neurons co‐express TrkB and TrkC, the tyrosine kinase
receptors for brain‐derived neurotrophic factor (BDNF) and neurotrophin‐3 (NT3). As NT3 …

trkB encodes a receptor tyrosine kinase activated by three neurotrophins—brain-derived
neurotrophic factor (BDNF), neurotrophin-3, and neurotrophin-4/5. In vivo, three isoforms of …

Neurotrophins are a family of growth factors playing key roles in the survival, development,
and function of neurons. The neurotrophins brain‐derived neurotrophic factor (BDNF) and …

A variety of findings seem to functionally link brainderived neurotrophic factor (BDNF))'and
neurotrophin3 (NT-3), while distinguishing both of these factors from the third member of the …

The neurotrophins brain‐derived neurotrophic factor (BDNF) and NT‐4/5 exert their trophic
effects on the nervous system via signaling through trkB receptors. These receptors occur as …

Members of the Trk tyrosine kinase family have recently been identified as functional
receptors of the NGF family of neurotrophins. Here we show the rat trkC locus to be complex …

Neurotrophins have multiple functions during peripheral nervous system development such
as controlling neuronal survival, target innervation and synaptogenesis. Neurotrophin …

Neurotrophins have long been thought to act as target-derived factors that regulate the
survival and differentiation of afferent neurons. Recently, brain-derived neurotrophic factor …

Neurotrophins regulate differentiation and survival of vertebrate neurons through binding to
members of the Trk family of receptor tyrosine kinases and to a common low affinity receptor …