Attenuating the effects of novel COVID-19 (SARS-CoV-2) infection-induced cytokine storm and the implications

AB Rowaiye, OA Okpalefe… - Journal of …, 2021 - Taylor & Francis
The COVID-19 pandemic constitutes an arduous global health challenge, and the
increasing number of fatalities calls for the speedy pursuit of a remedy. This review …

[HTML][HTML] Cytokine storm in COVID-19: immunopathogenesis and therapy

C Zanza, T Romenskaya, AC Manetti, F Franceschi… - Medicina, 2022 - mdpi.com
A cytokine storm is a hyperinflammatory state secondary to the excessive production of
cytokines by a deregulated immune system. It manifests clinically as an influenza-like …

Targeting cytokine storm to manage patients with COVID-19: a mini-review

N Roshanravan, F Seif, A Ostadrahimi… - Archives of medical …, 2020 - Elsevier
Corona Virus Disease 2019 (COVID-19) pandemic is rapidly spreading all over the world.
Excessive immune responses trigger life-threatening cytokine release syndrome (CRS) …

Emerging aspects of cytokine storm in COVID-19: The role of proinflammatory cytokines and therapeutic prospects

R Dharra, AK Sharma, S Datta - Cytokine, 2023 - Elsevier
COVID-19 has claimed millions of lives during the last 3 years since initial cases were
reported in Wuhan, China, in 2019. Patients with COVID-19 suffer from severe pneumonia …

[HTML][HTML] Cytokine storm in COVID-19: the current evidence and treatment strategies

Y Tang, J Liu, D Zhang, Z Xu, J Ji, C Wen - Frontiers in immunology, 2020 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) is the pathogen that causes
coronavirus disease 2019 (COVID-19). As of 25 May 2020, the outbreak of COVID-19 has …

Cytokine storm induced by SARS-CoV-2

P Song, W Li, J Xie, Y Hou, C You - Clinica chimica acta, 2020 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19), caused by the virus designated as severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread widely throughout the …

[HTML][HTML] Diverse immunological factors influencing pathogenesis in patients with COVID-19: a review on viral dissemination, immunotherapeutic options to counter …

AA Rabaan, SH Al-Ahmed, MA Garout, AM Al-Qaaneh… - Pathogens, 2021 - mdpi.com
The pathogenesis of coronavirus disease 2019 (COVID-19), caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), is still not fully unraveled. Though …

[HTML][HTML] The signal pathways and treatment of cytokine storm in COVID-19

L Yang, X Xie, Z Tu, J Fu, D Xu, Y Zhou - Signal transduction and …, 2021 - nature.com
Abstract The Coronavirus Disease 2019 (COVID-19) pandemic has become a global crisis
and is more devastating than any other previous infectious disease. It has affected a …

[HTML][HTML] Controlling cytokine storm is vital in COVID-19

L Tang, Z Yin, Y Hu, H Mei - Frontiers in immunology, 2020 - frontiersin.org
Corona virus disease 2019 (COVID-19) has caused a global outbreak and severely posed
threat to people's health and social stability. Mounting evidence suggests that …

[HTML][HTML] Immunopathogenesis and treatment of cytokine storm in COVID-19

JS Kim, JY Lee, JW Yang, KH Lee, M Effenberger… - Theranostics, 2021 - ncbi.nlm.nih.gov
Abstract Severe coronavirus disease 2019 (COVID-19) is characterized by systemic hyper-
inflammation, acute respiratory distress syndrome, and multiple organ failure. Cytokine …