[HTML][HTML] Role of ACE2 receptor and the landscape of treatment options from convalescent plasma therapy to the drug repurposing in COVID-19

P Kumar, AK Sah, G Tripathi, A Kashyap… - Molecular and cellular …, 2021 - Springer
Since the first case reports in Wuhan, China, the SARS-CoV-2 has caused a pandemic and
took lives of> 8, 35,000 people globally. This single-stranded RNA virus uses Angiotensin …

[HTML][HTML] Combination of angiotensin (1-7) agonists and convalescent plasma as a new strategy to overcome angiotensin converting enzyme 2 (ACE2) inhibition for the …

H Issa, AH Eid, B Berry, V Takhviji, A Khosravi… - Frontiers in …, 2021 - frontiersin.org
Coronavirus disease-2019 (COVID-19) pandemic caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) is currently the most concerning health problem …

[HTML][HTML] Angiotensin-converting enzyme 2 (ACE2): SARS-CoV-2 receptor and RAS modulator

J Bian, Z Li - Acta Pharmaceutica Sinica B, 2021 - Elsevier
Abstract The coronavirus disease 2019 (COVID-19) outbreak is caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). Angiotensin-converting enzyme 2 …

[HTML][HTML] Angiotensin-converting enzyme 2—at the heart of the COVID-19 pandemic

GY Oudit, K Wang, A Viveiros, MJ Kellner… - Cell, 2023 - cell.com
ACE2 is the indispensable entry receptor for SARS-CoV and SARS-CoV-2. Because of the
COVID-19 pandemic, it has become one of the most therapeutically targeted human …

[HTML][HTML] Recombinant human ACE2: potential therapeutics of SARS-CoV-2 infection and its complication

X Pang, Y Cui, Y Zhu - Acta Pharmacologica Sinica, 2020 - nature.com
Dear Editor, Since December 2019, severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) has caused a pneumonia outbreak in Wuhan city, China, followed by global …

Increasing host cellular receptor—angiotensin‐converting enzyme 2 expression by coronavirus may facilitate 2019‐nCoV (or SARS‐CoV‐2) infection

MW Zhuang, Y Cheng, J Zhang… - Journal of medical …, 2020 - Wiley Online Library
The ongoing outbreak of a new coronavirus (2019‐nCoV, or severe acute respiratory
syndrome coronavirus 2 [SARS‐CoV‐2]) has caused an epidemic of the acute respiratory …

[HTML][HTML] Understanding the role of ACE-2 receptor in pathogenesis of COVID-19 disease: a potential approach for therapeutic intervention

E Shirbhate, J Pandey, VK Patel, M Kamal… - Pharmacological …, 2021 - Springer
Angiotensin-converting enzyme (ACE) and its homologue, ACE2, are commonly allied with
hypertension, renin–angiotensin–aldosterone system pathway, and other cardiovascular …

[HTML][HTML] Advances in targeting ACE2 for developing COVID-19 therapeutics

S Suvarnapathaki, D Chauhan, A Nguyen… - Annals of biomedical …, 2022 - Springer
Since the onset of the coronavirus pandemic in December 2019, the SARS-CoV-2 virus has
accounted for over 6.3 million lives resulting in the demand to develop novel therapeutic …

[HTML][HTML] SARS-CoV-2 pandemic and research gaps: Understanding SARS-CoV-2 interaction with the ACE2 receptor and implications for therapy

PK Datta, F Liu, T Fischer, J Rappaport, X Qin - Theranostics, 2020 - ncbi.nlm.nih.gov
The COVID-19 pandemic is an emerging threat to global public health. While our current
understanding of COVID-19 pathogenesis is limited, a better understanding will help us …

[HTML][HTML] Soluble ACE2 as a potential therapy for COVID-19

S Krishnamurthy, RF Lockey… - American Journal of …, 2021 - journals.physiology.org
Soluble angiotensin-converting enzyme 2 (sACE2) could be a therapeutic option to treat
coronavirus disease 2019 (COVID-19) infection. Severe acute respiratory syndrome …