Inflammatory bowel diseases are a set of complex and chronic disorders that arise in
genetically predisposed individuals due to a lack of tolerance to the gut microflora. Although …

Inflammatory bowel diseases (IBDs) are thought to develop as a result of complex
interactions between host genetics, the immune system and the environment including the …

Conclusion In addition to the potential relationship between neutrophils, NETosis, CD
severity and neutrophil hetereogeneity may also represent another parameter that defines …

While barrier function and the effects of the intestinal microbiome have only recently moved
into the focus of inflammatory bowel disease research, the role of the innate and the …

The genetic architecture of the human host shapes the diversity and function of its stably
associated intestinal microflora. Innate immune receptors such as NOD2 or the …

Objectives: This review article describes the role of neutrophils in mucosal injury and the
resulting crypt abscesses characteristic of ulcerative colitis. We also review selected …

Inflammatory bowel diseases (IBD), including Crohn's disease and ulcerative colitis, are
featured by chronic intestinal inflammation, which is becoming increasingly prevalent in …

Humans have coevolved with a complex community of bacterial species also referred to as
the microbiome, which reciprocally provides critical contributions to human metabolism and …

Neutrophils are the most abundant leukocyte population in the human circulatory system
and are rapidly recruited to sites of inflammation. Neutrophils play a multifaceted role in …

Inflammatory bowel disease (IBD) results from a complex series of interactions between
susceptibility genes, the environment, and the immune system. The host microbiome, as well …