Capturing the biologic onset of inflammatory bowel diseases: impact on translational and clinical science

D Sorrentino, VQ Nguyen, MV Chitnavis - Cells, 2019 - mdpi.com
While much progress has been made in the last two decades in the treatment and the
management of inflammatory bowel diseases (IBD)—both ulcerative colitis (UC) and …

[HTML][HTML] Diversity of intestinal macrophages in inflammatory bowel diseases

AA Kühl, U Erben, LI Kredel, B Siegmund - Frontiers in immunology, 2015 - frontiersin.org
Macrophages as innate immune cells and fast responders to antigens play a central role in
protecting the body from the luminal content at a huge interface. Chronic inflammation in …

Genetics and innate and adaptive immunity in IBD

G Zanello, D Kevans, A Goethel, M Silverberg… - … , Gut Microbiota and …, 2014 - karger.com
Inflammatory bowel disease (IBD) is an abnormal inflammatory response within the gut to a
trigger that has yet to be identified. The family history in many patients, especially those with …

Pathophysiology of inflammatory bowel disease: innate immune system

A Saez, B Herrero-Fernandez, R Gomez-Bris… - International journal of …, 2023 - mdpi.com
Inflammatory bowel disease (IBD), comprising Crohn's disease (CD) and ulcerative colitis
(UC), is a heterogeneous state of chronic intestinal inflammation with no exact known cause …

Pursuing neutrophils: systematic scoping review on blood-based biomarkers as predictors of treatment outcomes in inflammatory bowel disease

D Magalhaes, L Peyrin-Biroulet… - Therapeutic …, 2023 - journals.sagepub.com
Background: Long-term management of inflammatory bowel diseases (IBD) is challenging
and the identification of reliable predictors for treatment outcomes is an unmet need …

Insights into IBD pathogenesis

DQ Shih, SR Targan - Current gastroenterology reports, 2009 - Springer
Inflammatory bowel disease (IBD), encompassing Crohn's disease (CD) and ulcerative
colitis (UC), is a chronic inflammatory disorder caused by dysregulated immune responses …

Microbiome and gut immunity: innate immune cells

T Strowig, S Thiemann, A Diefenbach - The Gut Microbiome in Health and …, 2018 - Springer
The innate immune system not only serves as a first line of defense against infections with
pathogenic microorganisms but also plays an important role in the balanced interplay with …

[HTML][HTML] Inflammatory bowel disease: recent advances on genetics and innate immunity

T Karantanos, M Gazouli - … publication of the Hellenic Society of …, 2011 - ncbi.nlm.nih.gov
The chronic inflammatory bowel diseases (IBD), Crohn's disease and ulcerative colitis, are
recognized as important causes of gastrointestinal disease in children and adults. Insight …

New insights into the pathophysiology of inflammatory bowel disease: microbiota, epigenetics and common signalling pathways

G Rogler, L Biedermann, M Scharl - Swiss medical weekly, 2018 - zora.uzh.ch
The exact pathophysiology of inflammatory bowel disease (IBD) is still unknown. However,
over the years important insights allowed the development of novel therapeutic approaches …

[引用][C] Innate immunity in inflammatory bowel disease

A Kaser, E Nieuwenhuis, L Glimcher, R Blumberg - Falk symposium, 2006