Inflammatory bowel diseases (IBDs) are diseases characterized by various degrees of inflammation involving the gastrointestinal tract. Ulcerative colitis and Crohn's disease are …
Risk factors that predispose an individual to loss of gut homeostasis include genetic variants and mutations, dysbiosis, immune dysregulation, and alterations in epithelial barrier function …
MW Khan, AA Kale, P Bere, S Vajjala… - Expert Review of …, 2012 - Taylor & Francis
Inflammatory bowel disease (IBD) is known for causing disturbed homeostatic balance among the intestinal immune compartment, epithelium and microbiota. Owing to the …
N Younis, R Zarif, R Mahfouz - Molecular biology reports, 2020 - Springer
Inflammatory bowel disease (IBD) is a chronic relapsing inflammatory disease that can involve any part of the gastrointestinal tract. It includes two main disorders: Crohn's disease …
M Sun, C He, Y Cong, Z Liu - Mucosal immunology, 2015 - Elsevier
The intestinal lumen harbors nearly 100 trillion commensal bacteria that exert crucial function for health. An elaborate balance between immune responses and tolerance to …
The intestines harbor over trillions of commensal bacteria, which co-evolve and form a mutualistic relationship with the host, with microbial-host interaction shaping immune …
S Cucchiara, L Stronati, M Aloi - Journal of clinical …, 2012 - journals.lww.com
Inflammatory bowel disease (IBD) is the result of an altered immune homeostasis within the intestinal mucosa against the gut microbiota, leading to chronic inflammation in genetically …
The inflammatory bowel diseases (IBDs) are among the most closely studied chronic inflammatory disorders that involve environmental, host genetic, and commensal microbial …
A Mizoguchi, E Mizoguchi - Journal of gastroenterology, 2008 - Springer
Accumulating data from animal models indicate that Inflammatory bowel disease (IBD) is mediated by a much more complicated mechanism than previously predicted. For example …