Innate immunity and inflammatory bowel disease: a review of clinical evidence and future application

K Katakura, H Watanabe, H Ohira - Clinical journal of gastroenterology, 2013 - Springer
Inflammatory bowel disease (IBD) is a chronic inflammatory disorder caused by
dysregulated immune responses in a genetically predisposed individual. Recent …

[HTML][HTML] Inflammatory bowel disease: pathogenesis

YZ Zhang, YY Li - World journal of gastroenterology: WJG, 2014 - ncbi.nlm.nih.gov
Inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, is
characterized by chronic relapsing intestinal inflammation. It has been a worldwide health …

Neutrophils and inflammatory metabolism in antimicrobial functions of the mucosa

EL Campbell, SP Colgan - Journal of Leucocyte Biology, 2015 - academic.oup.com
In this mini-review, we will discuss recent findings that implicate neutrophil infiltration and
function in establishing a metabolic environment to facilitate efficient pathogen clearance …

Interplay of intestinal microbiota and mucosal immunity in inflammatory bowel disease: a relationship of frenemies

H Chen, H Li, Z Liu - Therapeutic advances in …, 2020 - journals.sagepub.com
Inflammatory bowel diseases (IBDs), including ulcerative colitis and Crohn's disease, are
chronic inflammatory disorders of the gastrointestinal tract. With in-depth studies on the …

The intestinal microbiota in the pathogenesis of inflammatory bowel diseases: new insights into complex disease

KG Harris, EB Chang - Clinical Science, 2018 - portlandpress.com
Inflammatory bowel diseases (IBD) are a group of chronic diseases of increasing worldwide
prevalence characterized by gastrointestinal (GI) inflammation leading to debilitating …

Adherent-invasive Escherichia coli Exacerbates Antibiotic-associated Intestinal Dysbiosis and Neutrophil Extracellular Trap Activation

L Vong, CW Yeung, LJ Pinnell… - Inflammatory bowel …, 2016 - academic.oup.com
Background Antibiotic-associated disruption of the gut microbiota is a known risk factor for
Crohn's disease. This chronic inflammatory disorder results from aberrant host immune …

Immune and microbial mechanisms in the pathogenesis of inflammatory bowel disease

SB Snapper, DK Podolsky - UpToDate [online], 2008 - uptodate.com
The immune response has long been implicated in the pathogenesis of inflammatory bowel
disease (IBD), including both ulcerative colitis and Crohn disease. A vast body of literature …

What is wrong with granulocytes in inflammatory bowel diseases?

AP Levine, AW Segal - Digestive diseases, 2013 - karger.com
The neutrophil plays a central role in the acute inflammatory response, a crucial mechanism
required for the efficient clearance of invading microorganisms and antigenic material …

Microbiota in inflammatory bowel disease pathogenesis and therapy: is it all about diet?

DE Serban - Nutrition in clinical practice, 2015 - Wiley Online Library
Inflammatory bowel disease (IBD), including ulcerative colitis, Crohn's disease, and
unclassified IBD, continues to cause significant morbidity. While its incidence is increasing …

Highlights in inflammatory bowel disease–from bench to bedside

MA Engel, M Khalil, MF Neurath - Clinical Chemistry and Laboratory …, 2012 - degruyter.com
Approximately 3.6 million people in Europe and the USA suffer from recurrent auto-immune-
mediated inflammation of the gastrointestinal tract. Inflammatory bowel disease (IBD) …