Vaccination elicits immune responses capable of potently neutralizing SARS-CoV-2.
However, ongoing surveillance has revealed the emergence of variants harboring mutations …

Toward eradicating the COVID-19 pandemic, vaccines that induce high humoral and cellular
immune responses are essential. However, SARS-CoV-2 variants have begun to emerge …

All current vaccines for COVID-19 utilize ancestral SARS-CoV-2 spike with the goal of
generating protective neutralizing antibodies. The recent emergence and rapid spread of …

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is the causative infection of
a global pandemic that has led to more than 2 million deaths worldwide. The Moderna …

Administration of convalescent plasma or neutralizing monoclonal antibodies (mAbs) is a
potent therapeutic option for coronavirus disease 2019 (COVID-19) caused by severe acute …

SARS-CoV-2 and its variants continue to infect hundreds of thousands every day despite the
rollout of effective vaccines. Therefore, it is essential to understand the levels of protection …

The global spread of SARS-CoV-2/COVID-19 is devastating health systems and economies
worldwide. Recombinant or vaccine-induced neutralizing antibodies are used to combat the …

Coronaviruses are enveloped, positive-stranded RNA viruses that contain the largest known
RNA genomes to date. As severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

Initial COVID-19 vaccine candidates were based on the original sequence of SARS-CoV-2.
However, the virus has since accumulated mutations, among which the spike D614G is …

Several severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants have
arisen that exhibit increased viral transmissibility and partial evasion of immunity induced by …