Evidence for functional alterations in the skeletal muscle mechanoreflex and metaboreflex in hypertensive rats

AK Leal, MA Williams, MG Garry… - American Journal …, 2008 - journals.physiology.org
Exercise in hypertensive individuals elicits exaggerated increases in mean arterial pressure
(MAP) and heart rate (HR) that potentially enhance the risk for adverse cardiac events or …

[HTML][HTML] Influence of sex, menstrual cycle, and menopause status on the exercise pressor reflex

JR Smith, KE Koepp, JD Berg… - Medicine and science …, 2019 - ncbi.nlm.nih.gov
In this review, we highlight the underlying mechanisms responsible for the sex differences in
the exercise pressor reflex, and, importantly, the impact of sex hormones and menopausal …

[引用][C] The exercise pressor reflex: its cardiovascular effects, afferent mechanisms, and central pathways

JH Mitchell, MP Kaufman… - Annual review of …, 1983 - annualreviews.org
The neural control mechanisms responsible for the cardiovascular response to exercise are
not yet completely understood. Experimental evidence sugн gests two theories about the …

Exercise training prevents the exaggerated exercise pressor reflex in rats with chronic heart failure

HJ Wang, YX Pan, WZ Wang, L Gao… - Journal of Applied …, 2010 - journals.physiology.org
An exaggerated exercise pressor reflex (EPR) occurs in the chronic heart failure (CHF) state,
which contributes to exercise intolerance and excessive sympathoexcitation during exercise …

Cardiovascular regulation by skeletal muscle reflexes in health and disease

MN Murphy, M Mizuno, JH Mitchell… - American Journal of …, 2011 - journals.physiology.org
Heart rate and blood pressure are elevated at the onset and throughout the duration of
dynamic or static exercise. These neurally mediated cardiovascular adjustments to physical …

Reflex cardiovascular responses evoked by selective activation of skeletal muscle ergoreceptors

BG Leshnower, JT Potts, MG Garry… - Journal of applied …, 2001 - journals.physiology.org
It is well known that the exercise pressor reflex (EPR) is mediated by group III and IV skeletal
muscle afferent fibers, which exhibit unique discharge responses to mechanical and …

Skeletal muscle reflex-mediated changes in sympathetic nerve activity are abnormal in spontaneously hypertensive rats

M Mizuno, MN Murphy, JH Mitchell… - American Journal of …, 2011 - journals.physiology.org
In hypertension, the blood pressure response to exercise is exaggerated. We demonstrated
previously that this heightened pressor response to physical activity is mediated by an …

The TRPv1 receptor is a mediator of the exercise pressor reflex in rats

SA Smith, AK Leal, MA Williams… - The Journal of …, 2010 - Wiley Online Library
The skeletal muscle exercise pressor reflex (EPR) induces increases in heart rate (HR) and
mean arterial pressure (MAP) during physical activity. This reflex is activated during …

Role of the exercise pressor reflex in rats with dilated cardiomyopathy

SA Smith, PPA Mammen, JH Mitchell, MG Garry - Circulation, 2003 - Am Heart Assoc
Background—In heart failure, there is a sympathetically mediated hyperkinetic
cardiovascular response to exercise that limits tolerance to physical activity. Alterations in …

Capsaicin-based analgesic balm attenuates the skeletal muscle metaboreflex in healthy humans

LC Vianna, IA Fernandes, TC Barbosa… - Journal of applied …, 2018 - journals.physiology.org
The exercise pressor reflex (EPR) is comprised of group III and IV skeletal muscle afferents
and is one of the principal mediators of the cardiovascular response to exercise. In animals …