Clonogenically culturing and expanding CD34+ liver cancer stem cells in vitro

SC Park, C Zeng, B Tschudy-Seney… - Stem cells and …, 2015 - liebertpub.com
A large number of cancer stem cells (CSCs) have been isolated and identified; however,
none has been cultured in an unlimited manner in vitro without losing tumorigenicity and …

Identification and characterization of tumorigenic liver cancer stem/progenitor cells

S Ma, KW Chan, L Hu, TKW Lee, JYH Wo, IOL Ng… - Gastroenterology, 2007 - Elsevier
Background & Aims: Recent efforts in stem cell biology suggest that tumors are organized in
a hierarchy of heterogeneous cell populations and that the capability to maintain tumor …

Biology and clinical implications of CD133+ liver cancer stem cells

S Ma - Experimental cell research, 2013 - Elsevier
Hepatocellular carcinoma (HCC) is the most common primary malignant tumor of the liver,
accounting for 80%–90% of all liver cancers. The disease ranks as the fifth most common …

[HTML][HTML] Novel therapeutic strategies for targeting liver cancer stem cells

N Oishi, XW Wang - International Journal of Biological Sciences, 2011 - ncbi.nlm.nih.gov
The cancer stem cell (CSC) hypothesis was first proposed over 40 years ago. Advances in
CSC isolation were first achieved in hematological malignancies, with the first CSC …

CD34+ Liver Cancer Stem Cells Were Formed by Fusion of Hepatobiliary Stem/Progenitor Cells with Hematopoietic Precursor-Derived Myeloid Intermediates

C Zeng, Y Zhang, SC Park, JR Eun… - Stem cells and …, 2015 - liebertpub.com
A large number of cancer stem cells (CSCs) were identified and characterized; however, the
origins and formation of CSCs remain elusive. In this study, we examined the origination of …

[PDF][PDF] Surface markers of hepatocellular cancer stem cells and their clinical potential

D Feng, N Wang, J Hu, W Li - Neoplasma, 2014 - academia.edu
Cancer stem cells (CSCs) are a small subpopulation of cells within tumors with capabilities
of self-renewal, differentiation, and tumorigenicity when transplanted into immune …

[HTML][HTML] Liver cancer stem cells: Recent progress in basic and clinical research

T Yamashita, S Kaneko - Regenerative Therapy, 2021 - Elsevier
The cancer stem cell (CSC) hypothesis was proposed over 4 decades ago and states that
tumor growth is maintained by a small subset of cancer cells analogous to normal tissue …

Cancer stem cells in hepatocellular carcinoma: Recent progress and perspective

T Chiba, A Kamiya, O Yokosuka, A Iwama - Cancer letters, 2009 - Elsevier
Although the “cancer stem cell (CSC)” hypothesis was first proposed roughly 50years ago,
recent progress in stem cell biology and technologies has successfully achieved the …

Hierarchical potential differentiation of liver cancer stem cells.

W Zhang, D Mu, K Feng - Advances in Clinical & …, 2017 - search.ebscohost.com
Hepatocellular carcinoma (HCC) is one of the most malignant tumors in Chinese people and
offers poor prognosis. Tumor tissue, like normal tissue, is hierarchically differentiated. Thus …

Biology of hepatic cancer stem cells

CM Tong, S Ma, XY Guan - Journal of Gastroenterology and …, 2011 - Wiley Online Library
Hepatocellular carcinoma (HCC) is the most commonly diagnosed malignancy of the liver
and is the third most frequent cause of cancer death worldwide. Although advances in HCC …