Ilaprazole is a novel proton pump inhibitor and this is the first study to investigate the
pharmacokinetics, pharmacodynamics and safety of intravenous ilaprazole in healthy …

Pantoprazole (PAN), a selective proton pump inhibitor, is used clinically as a racemic
mixture for the treatment of acid-related gastrointestinal disorders. To investigate its …

AIM: To set up a method to determine the blood concentration of lansoprazole and its
metabolites 5'-lansoprazole and lansoprazole sulphone. METHODS: The blood …

Aripiprazole, a partial agonist of dopamine D 2 receptors, is primarily metabolized to active
dehydroaripiprazole and then converted to its urinary metabolites 1-(2, 3-dichlorophenyl) …

Analytical and semipreparative high-performance liquid chromatography (HPLC)
enantioseparation of the proton-pump inhibitor omeprazole (OME) and its potential organic …

Objective: To develop a simple and accurate RP-HPLC method for simultaneous estimation
of organic impurities, enantiomer and assay of Dexlansoprazole, proposed method was …

A selective, sensitive, high pressure liquid chromatography–positive electrospray ionization
tandem mass spectrometry method was developed and validated for the quantification of …

This work reports the result of the enantioselective disposition of pantoprazole, omeprazole,
and lansoprazole in a same group of Brazilian health subjects. Ten nongenotyped healthy …

Abstract Background and Objective This study was performed in healthy Chinese subjects to
evaluate the safety and pharmacokinetic/pharmacodynamic characteristics of a novel …