Pathogenesis of uveitis in Ebola virus disease survivors: evolving understanding from outbreaks to animal models

C Hartley, JC Bavinger, S Kuthyar, JG Shantha, S Yeh - Microorganisms, 2020 - mdpi.com
Ebola virus disease (EVD) and emerging infectious disease threats continue to threaten life,
prosperity and global health security. To properly counteract EVD, an improved …

Clinical manifestations and pathogenesis of uveitis in Ebola virus disease survivors

S Yeh, JG Shantha, B Hayek, I Crozier… - Ocular Immunology and …, 2018 - Taylor & Francis
In the wake of the international Ebola virus disease (EVD) outbreak from 2014 to 2016,
thousands of EVD survivors are at-risk of ophthalmic manifestations, as well as systemic …

Ophthalmic manifestations and causes of vision impairment in Ebola virus disease survivors in Monrovia, Liberia

JG Shantha, I Crozier, BR Hayek, BB Bruce, C Gargu… - Ophthalmology, 2017 - Elsevier
Purpose To describe the ocular findings, visual impairment, and association of structural
complications of uveitis with visual impairment in a cohort of survivors of Ebola virus disease …

Persistent intraocular Ebola virus RNA is associated with severe uveitis in a convalescent rhesus monkey

G Worwa, TK Cooper, S Yeh, JG Shantha… - Communications …, 2022 - nature.com
Despite increasing evidence that uveitis is common and consequential in survivors of Ebola
virus disease (EVD), the host-pathogen determinants of the clinical phenotype are …

Factors associated with uveitis among Ebola survivors in the PREVAIL III study

AO Eghrari, B Burkholder, R Ross… - … & Visual Science, 2017 - iovs.arvojournals.org
Purpose: Survivors of Ebola virus disease frequently experience intraocular inflammation in
the months following systemic infection. Little is known regarding the factors associated with …

[HTML][HTML] Burden, timing, and outcomes of uveitis from a retrospective cohort of Ebola survivors in Sierra Leone

MJ Vandy, J Chang, JG Mattia, B Molleh… - … & Visual Science, 2018 - iovs.arvojournals.org
Purpose: Uveitis has emerged as a sight-threatening sequelae of Ebola virus disease
(EVD). We describe the prevalence of ocular diagnoses, severity of uveitis, and the timing of …

An update on ocular complications of Ebola virus disease

JG Shantha, I Crozier, S Yeh - Current opinion in ophthalmology, 2017 - journals.lww.com
Uveitis is the most common ophthalmic finding in EVD survivors and can lead to vision loss.
Further studies into the clinical manifestations and mechanisms of disease are needed to …

Ebola virus tropism in ex vivo cynomolgus macaque ocular tissues

MJ Matson, T Bushmaker, DP Scott… - The Journal of …, 2023 - academic.oup.com
Ocular complications of Ebola virus disease are well-documented and long-term sequelae
in survivors are common and lead to considerable morbidity. However, little is currently …

Development of a screening eye clinic for Ebola virus disease survivors: lessons learned and rapid implementation at ELWA Hospital in Monrovia, Liberia 2015

JG Shantha, BR Hayek, I Crozier, C Gargu… - PLoS neglected …, 2019 - journals.plos.org
Background In the wake of the West African Ebola virus disease (EVD) outbreak of 2014–
2016, thousands of EVD survivors began to manifest a constellation of systemic and …

Ocular complications in Ebola virus disease survivors: the importance of continuing care in West Africa

DE Berry, AL Li, S Yeh, JG Shantha - Expert review of …, 2019 - Taylor & Francis
ABSTRACT Introduction: The largest Ebola virus (EBOV) outbreak occurred from 2013 to
2016 in West Africa and consequently resulted in the largest cohort of Ebola virus disease …