With progress in genome-wide association studies of depression, from identifying zero hits in~ 16 000 individuals in 2013 to 223 hits in more than a million individuals in 2020 …
Abstract Purpose of Review We will describe the success of recent genome-wide association studies that identify genetic variants associated with depression and outline the …
There have been several recent studies addressing the genetic architecture of depression. This review serves to take stock of what is known now about the genetics of depression, how …
BackgroundIt has been well established that both genes and non-shared environment contribute substantially to the underlying aetiology of major depressive disorder (MDD). A …
Background The genetics of depression has been explored in genome-wide association studies that focused on either major depressive disorder or depressive symptoms with …
Major depressive disorder (MDD) is common and moderately heritable. Recurrence and early age at onset characterize cases with the greatest familial risk. Major depressive …
BACKGROUND: Depression is a heritable trait that exists on a continuum of varying severity and duration. Yet, the search for genetic variants associated with depression has had few …
The genetic dissection of major depressive disorder (MDD) ranks as one of the success stories of psychiatric genetics, with genome-wide association studies (GWAS) identifying …
Major depressive disorder (MDD) is a common illness accompanied by considerable morbidity, mortality, costs, and heightened risk of suicide. We conducted a genome-wide …