Molecular diagnostics have an established role for the diagnosis of leptospirosis and
provide an actionable diagnosis in the acute setting. The use of real-time reverse …

Prompt laboratory diagnosis of leptospirosis infection facilitates patient management and
initiation of therapy. A cost effective real-time PCR assay using SYBR Green I was …

Leptospirosis is a globally important zoonotic disease and an important public health
problem in developing countries. Early diagnosis is essential because antibiotic treatment is …

Definitive diagnosis of leptospirosis has traditionally depended upon the isolation of
leptospires from clinical specimens or the demonstration of seroconversion in paired acute …

Leptospirosis is considered an underdiagnosed disease. Although several PCR-based
methods are currently in use, there is little information on their comparability. In this study …

Background Reference diagnostic tests for leptospirosis include nucleic acid amplification
tests, bacterial culture, and microscopic agglutination testing (MAT) of acute and …

Available serological diagnostics do not allow the confirmation of clinically suspected
leptospirosis at the early acute phase of illness. Several conventional and real-time PCRs …

Background Leptospirosis is an emerging infectious disease. The differential diagnosis of
leptospirosis is difficult due to the varied and often" flu like" symptoms which may result in a …

Background Bacteria of the genus Leptospira, the causative agents of leptospirosis, are
categorized into pathogenic and non-pathogenic species. However, the benefit of using a …

Aim The aim of the study was to detect the leptospiral DNA by PCR method and to compare
the results of PCR with other available diagnostic methods used for diagnosis of suspected …