Amino-bisphosphonates such as zoledronic acid (ZA) can possibly ameliorate or prevent
severe COVID-19 disease by at least three distinct mechanisms:(1) as immunostimulants …

The emergence of new SARS-CoV-2 variants continues to pose an enormous public health
concern. The SARS-CoV-2 infection disrupted host immune response accounting for …

The on-going pandemic of COVID-19 wreaked by a viral infection of SARS-CoV-2, has
generated a catastrophic plight across the globe. Interestingly, one of the hallmarks of …

The World Health Organization has announced COVID-19 as a pandemic in March 2020.
COVID-19 is an infectious disease caused by the severe acute respiratory syndrome …

Phosphodiesterase 4 (PDE4) inhibitors are immunomodulatory drugs approved to treat
diseases associated with chronic inflammatory conditions, such as COPD, psoriasis and …

ABSTRACT Introduction SARS-CoV-2, the virus that causes COVID-19, elicits a variety of
host responses ranging from asymptomatic or mild illness in most people, to severe disease …

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is highly infectious,
spreading swiftly from man to man which has not been previously recognized in humans …

Coronavirus disease 2019 (COVID-19), which is caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), is spreading rapidly throughout the world. Although …

Aims Over the past few years, AI has been considered as potential important area for
improving drug development and in the current urgent need to fight the global COVID-19 …

SARS-CoV-2 is causing the coronavirus disease 2019 (COVID-19) pandemic, for which
effective pharmacological therapies are needed. SARS-CoV-2 induces a shift of the host cell …