The question of whether melanins are photoprotecting and/or photosensitizing in human
skin cells continues to be debated. To evaluate the role of melanin upon UVA irradiation …

The goal of this investigation was to correlate the melanin content in human pigmentary cells
with the generation of UVB‐induced photoproducts and to examine the relationship between …

Cultured melanocytes originating from persons with different skin phototypes were utilized
for measurement of endonuclease sensitive sites induced by UVB and the determination of …

Melanin is both photosensitizer and photoprotector. Skin cancer rates decrease with
increasing constitutive pigmentation, yet the pigment has been shown to be photoreactive …

Short-term and long-term survival of cultured neonatal foreskin melanocytes from black and
white individuals were assessed following a single exposure to simulated sunlight or …

Melanin is thought to serve in photoprotection. To investigate this, we have compared the
responses of cultured human melanocytes derived from different pigmentary phenotypes …

The induction of DNA breaks by UVA (320–400 nm) in the nucleus of normal human
melanocytes in culture was investigated using single cell gel electrophoresis, also called the …

Repetitive suberythemal UVA and/or UVB exposures were used to generate comparable UV‐
induced tans in human skin over the course of 2 weeks. To evaluate the potential …

Although the ability of UV irradiation to induce pigmentation in vivo and in vitro is well
documented, the intracellular signals that trigger this response are poorly understood. We …

Cloudman S91 mouse melanoma cells vary in constitutive and inducible melanin levels.
Survival, mutation induction and DNA damage were quantitated after exposure to UVB, UVA …