Inappropriate medication is a major cause of adverse drug reactions in elderly patients

CM Lindley, MP Tully, V Paramsothy… - Age and ageing, 1992 - academic.oup.com
To determine the extent to which adverse drug reactions (ADRs) in elderly patients admitted
to hospital are due to inappropriate prescribing, we examined 416 successive admissions of …

Self-reported adverse drug reactions and related resource use: a study of community-dwelling persons 65 years of age and older

EA Chrischilles, ET Segar… - Annals of internal medicine, 1992 - acpjournals.org
▪ Objective: To describe the incidence and health resource consequences of self-reported
adverse drug reactions (ADRs) and their relation to self-perceived health, number of …

Inappropriate medication use as a risk factor for self‐reported adverse drug effects in older adults

EA Chrischilles, R VanGilder, K Wright… - Journal of the …, 2009 - Wiley Online Library
OBJECTIVES: To determine the association between inappropriate medication use and self‐
reported adverse drug effects (ADEs). DESIGN: Prospective cohort study with three annual …

Fatal adverse drug events: the paradox of drug treatment

I Buajordet, J Ebbesen, J Erikssen… - Journal of internal …, 2001 - Wiley Online Library
Buajordet I, Ebbesen J, Erikssen J, Brørs O, Hilberg T (The Norwegian Medicines Agency,
Oslo; Central Hospital of Akershus, Nordbyhagen; Ullevaal University Hospital and National …

Timing of new black box warnings and withdrawals for prescription medications

KE Lasser, PD Allen, SJ Woolhandler, DU Himmelstein… - Jama, 2002 - jamanetwork.com
ContextRecently approved drugs may be more likely to have unrecognized adverse drug
reactions (ADRs) than established drugs, but no recent studies have examined how …

The costs of adverse drug events in community hospitals

BL Hug, C Keohane, DL Seger, C Yoon… - The joint commission …, 2012 - Elsevier
Article-at-a-Glance Background Adverse drug events (ADEs) occur often in hospitals,
causing high morbidity and a longer length of stay (LOS), and are costly. However, most …

The costs associated with adverse drug events among older adults in the ambulatory setting

TS Field, BH Gilman, S Subramanian, JC Fuller… - Medical care, 2005 - journals.lww.com
Background: Reducing the rate of adverse drug events in the ambulatory setting may require
large investments in quality improvement efforts and technologic innovations. Little evidence …

The risk of adverse drug events and hospital-related morbidity and mortality among older adults with potentially inappropriate medication use

RL Page II, JM Ruscin - The American journal of geriatric pharmacotherapy, 2006 - Elsevier
BACKGROUND:: Inappropriate medication prescribing is a significant problem among older
adults that may contribute to increased morbidity and mortality as well as increased costs of …

Generic versus brand-name drugs used in cardiovascular diseases

L Manzoli, ME Flacco, S Boccia, E D'Andrea… - European journal of …, 2016 - Springer
This meta-analysis aimed to compare the efficacy and adverse events, either serious or
mild/moderate, of all generic versus brand-name cardiovascular medicines. We searched …

Assessing the FDA via the anomaly of off-label drug prescribing

AT Tabarrok - The Independent Review, 2000 - JSTOR
It is commonly thought that the US Food and Drug Administration (FDA) regulates the use of
all pharmaceutical drugs in the United States. In fact, most hospital patients are given drugs …