Influence of a mutation in the putative nucleotide binding site of the nitrogen regulatory protein NTRC on its positive control function
S Austin, C Kundrot, R Dixon - Nucleic acids research, 1991 - academic.oup.com
A mutation, serine 170 to alanine, in the proposed ATP binding site of the activator protein
NTRC prevents transcriptional activation at σ 54-dependent promoters both in vivo and in …
NTRC prevents transcriptional activation at σ 54-dependent promoters both in vivo and in …
Substitutions at a single amino acid residue in the nitrogen‐regulated activator protein NTRC differentially influence its activity in response to phosphorylation
R Dixon, T Eydmann, N Henderson… - Molecular …, 1991 - Wiley Online Library
Four substitutions at serine residue 160 which increase the activity of the σ54‐dependent
activator protein NTRC in the absence of NTRB have been analysed in detail. Mutagenesis …
activator protein NTRC in the absence of NTRB have been analysed in detail. Mutagenesis …
Glutamate at the site of phosphorylation of nitrogen-regulatory protein NTRC mimics aspartyl-phosphate and activates the protein
The NTRC protein of enteric bacteria is an enhancer-binding protein that activates
transcription by the σ 54-holoenzyme form of RNA polymerase under nitrogen-limiting …
transcription by the σ 54-holoenzyme form of RNA polymerase under nitrogen-limiting …
Interaction of purified NtrC protein with nitrogen regulated promoters from Klebsiella pneumoniae
The product of the Klebsiella pneumoniae nitrogen regulatory gene ntrC has been purified
and shown to be a dimeric protein of subunit molecular weight 54Kd, designated NtrC. In an …
and shown to be a dimeric protein of subunit molecular weight 54Kd, designated NtrC. In an …
Repressor forms of the enhancer-binding protein NtrC: some fail in coupling ATP hydrolysis to open complex formation by σ54-holoenzyme
AK North, DS Weiss, H Suzuki, Y Flashner… - Journal of molecular …, 1996 - Elsevier
NtrC (nitrogen regulatory protein C) is a bacterial enhancer-binding protein that activates
transcription by catalyzing isomerization of closed complexes between σ54-holoenzyme and …
transcription by catalyzing isomerization of closed complexes between σ54-holoenzyme and …
The effect on the function of the transcriptional activator NtrC from Klebsiella pneumoniae of mutations in the DNA-recognition helix
A Contreras, M Drummond - Nucleic acids research, 1988 - academic.oup.com
We have constructed mutations in what we predict to be the DNA-recognition helix of
Klebsiella pneumoniae NtrC, which regulates transcription from promoters under global …
Klebsiella pneumoniae NtrC, which regulates transcription from promoters under global …
Constitutive forms of the enhancer-binding protein NtrC: evidence that essential oligomerization determinants lie in the central activation domain
Y Flashner, DS Weiss, J Keener, S Kustu - Journal of molecular biology, 1995 - Elsevier
Nitrogen regulatory protein C (NtrC) is a bacterial enhancer-binding protein that activates
transcription by the σ54-holoenzyme. To activate transcription, NtrC must hydrolyze ATP, a …
transcription by the σ54-holoenzyme. To activate transcription, NtrC must hydrolyze ATP, a …
Mechanism of transcriptional activation by NtrC
SC Porter, AK North, S Kustu - Two‐Component Signal …, 1995 - Wiley Online Library
In the case of nitrogen regulatory protein C (NtrC), both nucleotide hydrolysis and
transcriptional activation depend on phosphorylation of an aspartate residue in the N …
transcriptional activation depend on phosphorylation of an aspartate residue in the N …
“Switch I” mutant forms of the bacterial enhancer-binding protein NtrC that perturb the response to DNA
D Yan, S Kustu - Proceedings of the National Academy of …, 1999 - National Acad Sciences
NtrC (nitrogen regulatory protein C) is a bacterial enhancer-binding protein of 469 residues
that activates transcription by σ54-holoenzyme. A region of its transcriptional activation …
that activates transcription by σ54-holoenzyme. A region of its transcriptional activation …
Mechanism of activation of a response regulator: interaction of NtrC-P dimers induces ATPase activity
I Mettke, U Fiedler, V Weiss - Journal of bacteriology, 1995 - Am Soc Microbiol
NtrC is the transcriptional activator for nitrogen-regulated promoters and, as a response
regulator, belongs to the protein family of two-component systems. The activity of all …
regulator, belongs to the protein family of two-component systems. The activity of all …