Short-term exposure to ambient ozone is associated with adverse cardiovascular effects,
with inconsistent evidence on the molecular mechanisms. We conducted a longitudinal …

DNA methylation is implicated in tissue-specific gene expression and genomic imprinting. It
is modulated by environmental factors, especially nutrition. Modified DNA methylation …

The level of epigenetic DNA methylation is an important factor in the pathogenesis of various
human diseases. As smoking may influence DNA methylation, we investigated the effect of …

Metabolic syndrome (MetS) has been postulated to increase the risk for type 2 diabetes,
cardiovascular disease and cancer. Adipose tissue (AT) plays an important role in metabolic …

ABSTRACT DNA methylation (DNAm) is one of the most studied epigenetic modifications.
DNAm has emerged as a key biological mechanism and biomarkers to test associations …

Maternal smoking causes lower birth weight, birth defects, and other adverse pregnancy
outcomes. Epidemiological evidence over the past four decades has grown stronger and the …

Objective Obesity is driven by modifiable lifestyle factors whose effects may be mediated by
epigenetics. Therefore, we investigated lifestyle effects on blood DNA methylation in …

Background With epigenome-wide mapping of DNA methylation, a number of novel smoking-
associated loci have been identified. Objectives We aimed to assess dose–response …

Long-term exposure to air pollution has been associated with several adverse health effects
including cardiovascular, respiratory diseases and cancers. However, underlying molecular …

Background: Epidemiological studies have reported associations between particulate matter
(PM) concentrations and cancer and respiratory and cardiovascular diseases. DNA …