Epidemiological studies have demonstrated that genetic, environmental, behavioral, and
clinical factors contribute to cardiovascular disease development. How these risk factors …

Environmental pollution is one of the main causes of human cancer. Exposures to
environmental carcinogens result in genetic and epigenetic alterations which induce cell …

Rationale: Exposure to particulate air pollution has been related to increased hospitalization
and death, particularly from cardiovascular disease. Lower blood DNA methylation content …

The knowledge about the effects of environmental temperature on human epigenome is a
potential key to understand the health impacts of temperature and to guide acclimation …

Cigarette smoking impacts DNA methylation, but the investigation of sex-specific features of
lung tissue DNA methylation in smokers has been limited. Women appear more susceptible …

Dysregulation of circulating lipids is a central element for the metabolic syndrome. However,
it is not well established whether human subcutaneous adipose tissue is affected by or affect …

Air pollution is a serious threat to our health and has become one of the major causes of
many diseases including cardiovascular disease, respiratory disease, and cancer. The …

Background: We examined whether the effect of maternal smoking during pregnancy on
birthweight of the offspring was mediated by smoking-induced changes to DNA methylation …

Physical activity is a strong stimulus influencing the overall physiology of the human body.
Exercises lead to biochemical changes in various tissues and exert an impact on gene …

Background: Recent technological advances in epigenome profiling have led to an
increasing number of studies investigating the role of the epigenome in obesity. There is …