Targeted cancer therapy using engineered exosome as a natural drug delivery vehicle

H Gomari, M Forouzandeh Moghadam… - OncoTargets and …, 2018 - Taylor & Francis
Purpose Exosomes are small 30–100 nm vesicles secreted by various cell types. They are
released by most cell types, indicating their important role in physiological and pathological …

Exosomes: cell-derived nanoplatforms for the delivery of cancer therapeutics

H Kim, EH Kim, G Kwak, SG Chi, SH Kim… - International journal of …, 2020 - mdpi.com
Exosomes are cell-secreted nanovesicles that naturally contain biomolecular cargoes such
as lipids, proteins, and nucleic acids. Exosomes mediate intercellular communication …

Recent advances in exosome-based drug delivery for cancer therapy

H Kim, H Jang, H Cho, J Choi, KY Hwang, Y Choi… - Cancers, 2021 - mdpi.com
Simple Summary Exosomes derived from various sources can deliver therapeutic agents
such as small molecule drugs, nucleic acids, and proteins to cancer cells by passive or …

Exosome as a delivery vehicle for cancer therapy

B Moon, S Chang - Cells, 2022 - mdpi.com
Exosomes are small extracellular vesicles that are naturally produced and carry
biomolecules such as proteins, microRNAs, and metabolites. Because of their small size …

Exosomes as drug carriers in anti-cancer therapy

L Chen, L Wang, L Zhu, Z Xu, Y Liu, Z Li… - Frontiers in Cell and …, 2022 - frontiersin.org
Over the years, there has been a high demand for developing new safe and effective drug
carriers for cancer therapy. Emerging studies have indicated that exosomes can serve as …

Exosome-based delivery strategies for tumor therapy: an update on modification, loading, and clinical application

Q Yang, S Li, H Ou, Y Zhang, G Zhu, S Li… - Journal of …, 2024 - Springer
Malignancy is a major public health problem and among the leading lethal diseases
worldwide. Although the current tumor treatment methods have therapeutic effect to a certain …

[HTML][HTML] Exosomes as drug carriers for cancer therapy and challenges regarding exosome uptake

X Zhao, D Wu, X Ma, J Wang, W Hou… - Biomedicine & …, 2020 - Elsevier
With the development of biomedicine, exosomes are rapidly developing as a new therapy
for tumors. As biological carriers, exosomes possess biological activity and can transport …

[HTML][HTML] Engineering exosomes: a new direction for anticancer treatment

B You, W Xu, B Zhang - American journal of cancer research, 2018 - ncbi.nlm.nih.gov
Currently, lacks of specificity and effectiveness remain the main drawbacks of clinical cancer
treatment. Despite therapeutic advances in recent decades, clinical outcomes remain poor …

Engineered exosomes from different sources for cancer-targeted therapy

M Zhang, S Hu, L Liu, P Dang, Y Liu, Z Sun… - Signal transduction and …, 2023 - nature.com
Exosome is a subgroup of extracellular vesicles, which has been serving as an efficient
therapeutic tool for various diseases. Engineered exosomes are the sort of exosomes …

Bioinspired exosome-mimetic nanovesicles for targeted delivery of chemotherapeutics to malignant tumors

SC Jang, OY Kim, CM Yoon, DS Choi, TY Roh, J Park… - ACS …, 2013 - ACS Publications
Exosomes, the endogenous nanocarriers that can deliver biological information between
cells, were recently introduced as new kind of drug delivery system. However, mammalian …