Background A fundamental challenge for understanding neuropsychiatric disease is
identifying sources of individual differences in psychopathology, especially when there is …

Background This study investigated characteristic large-scale brain changes in
schizophrenia. Numerous imaging studies have demonstrated brain changes in …

Brain network alterations have increasingly been implicated in schizophrenia (SCZ), bipolar
disorder (BD), and major depressive disorder (MDD). However, little is known about the …

Importance The clinical heterogeneity of schizophrenia has hindered neurobiological
investigations aimed at identifying neural correlates of the disorder. Objective To identify …

Schizophrenia (SZ) is a severe mental illness with high heritability and complex etiology.
Mounting evidence from neuroimaging has implicated disrupted brain network connectivity …

Neuroimaging studies have demonstrated that the phenomenology of schizophrenia maps
onto diffuse alterations in large-scale functional and structural brain networks. However, the …

Background: The human brain is organized into functionally distinct modules of which
interactions constitute the human functional connectome. Accumulating evidence has …

BACKGROUND: Schizophrenia is hypothesized to involve disordered connectivity between
brain regions. Currently, there are no direct measures of brain connectivity; functional and …

Neuroimaging studies of psychotic disorders have demonstrated abnormalities in structural
and functional connectivity involving widespread brain networks. However, these group …

Background: Schizophrenia is characterized by a lack of integration between thought,
emotion, and behavior. A disruption in the connectivity between brain processes may …