Bacterial DNA containing immunostimulatory motifs (CpG) induces the development of a
TH1 immune response. Since protection against Toxoplasma gondii is correlated with this …

Infection with the intracellular protozoan parasite Toxoplasma gondii causes serious public
health problems to both humans and livestock and of great economic impact worldwide …

Synthetic oligodeoxynucleotides containing unmethylated CpG motifs (CpG-ODN) have
been characterized as Th1-promoting immunopotentiators, an adjuvant activity desirable for …

Toxoplasma gondii (T. gondii) is one of the most successful intracellular protozoan parasites
on earth and highly prevalent in most warm-blooded vertebrates. There are no drugs that …

Th1-type immune response plays a critical role in resistance to Trypanosoma cruzi infection.
We asked whether a synthetic oligodeoxynucleotide that contains immunostimulatory CpG …

Immunostimulatory CpG DNA is recognized by cells of the innate immune system through
Toll-like receptor 9 (TLR9). Synthetic CpG oligonucleotides (CpG-ODN) belong to the most …

Unmethylated CpG dinucleotides have been found to stimulate general immune responses
in mammals. CpG motifs have further been shown to be potent adjuvants when used in …

Immunization of BALB/c mice with an expression genomic library of Toxoplasma gondii
induces a Th1-type immune response, with recognition of several T. gondii proteins (21 to …

To investigate the vaccine potential of multi-epitope vaccines against toxoplasmosis, a multi-
epitope DNA vaccine, eukaryotic plasmid pcDNA3. 1/T-ME expressing six antigen segments …

Protection against a challenge infection with Toxoplasma gondii VEG strain oocysts was
examined in pigs after vaccination with T. gondii RH strain tachyzoites with or without a …