[HTML][HTML] A brief overview of SARS-CoV-2 infection and its management strategies: a recent update

A Das, S Pathak, M Premkumar… - Molecular and Cellular …, 2023 - Springer
The COVID-19 pandemic has become a global health crisis, inflicting substantial morbidity
and mortality worldwide. A diverse range of symptoms, including fever, cough, dyspnea, and …

Understanding COVID-19 pandemic: molecular mechanisms and potential therapeutic strategies. An evidence-based review

R Hanna, S Dalvi, T Sălăgean, ID Pop… - Journal of …, 2021 - Taylor & Francis
Abstract Initially, the SARS-CoV-2 virus was considered as a pneumonia virus; however, a
series of peer reviewed medical papers published in the last eight months suggest that this …

Review on therapeutic targets for COVID-19: insights from cytokine storm

ML de Mélo Silva Júnior, LMA de Souza… - Postgraduate …, 2021 - academic.oup.com
Introduction Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been
caused the greatest pandemic of our century. Many of the deaths related to it are due to a …

The emergence of COVID-19 as a global pandemic: Understanding the epidemiology, immune response and potential therapeutic targets of SARS-CoV-2

S Muralidar, SV Ambi, S Sekaran, UM Krishnan - Biochimie, 2020 - Elsevier
An acute respiratory disease caused by a severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) that surfaced in China in late 2019, continues to spread rapidly across the …

[HTML][HTML] Recent advances in pathophysiology, drug development and future perspectives of SARS-CoV-2

DD Singh, I Han, EH Choi, DK Yadav - Frontiers in cell and …, 2020 - frontiersin.org
The coronavirus (SARS-CoV-2) pandemic is a rapidly transmitting and highly pathogenic
disease. The spike protein of SARS-CoV-2 binds to the surface of angiotensin-converting …

[HTML][HTML] SARS-coV-2 treatment approaches: numerous options, no certainty for a versatile virus

S Iacob, DG Iacob - Frontiers in Pharmacology, 2020 - frontiersin.org
SARS-CoV-2 is the most recent coronavirus which crossed the species barrier in 2019 and
provoked a still ongoing and dangerous pandemic known as coronavirus disease 2019 …

[HTML][HTML] Current therapeutics for COVID-19, what we know about the molecular mechanism and efficacy of treatments for this novel virus

D Narayanan, T Parimon - International Journal of Molecular Sciences, 2022 - mdpi.com
Severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) has caused significant
morbidity and mortality worldwide. Though previous coronaviruses have caused substantial …

SARS-CoV-2: pathogenesis, therapeutics, variants, and vaccines

X Li, Z Mi, Z Liu, P Rong - Frontiers in Microbiology, 2024 - frontiersin.org
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), emerged in December 2019 with staggering economic fallout …

[HTML][HTML] SARS-CoV-2: From structure to pathology, host immune response and therapeutic management

G Mihaescu, MC Chifiriuc, C Iliescu, CO Vrancianu… - Microorganisms, 2020 - mdpi.com
Coronaviruses are large, enveloped viruses with a single-stranded RNA genome, infecting
both humans and a wide range of wild and domestic animals. SARS-CoV-2, the agent of the …

An updated insight into the molecular pathogenesis, secondary complications and potential therapeutics of COVID-19 pandemic

S Jamwal, A Gautam, J Elsworth, M Kumar, R Chawla… - Life sciences, 2020 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) is an unprecedented disease caused by
highly pathogenic SARS-CoV-2 and characterized by extreme respiratory deterrence …