Clinical characteristics, diagnosis, and therapeutics of covid-19: A review

N Xie, W Zhang, J Chen, F Tian, J Song - Current Medical Science, 2023 - Springer
The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that suddenly
emerged at the end of December 2019 and caused coronavirus disease 2019 (COVID-19) …

COVID-19: in the eye of the cytokine storm

R De la Rica, M Borges, M Gonzalez-Freire - Frontiers in immunology, 2020 - frontiersin.org
The dysregulated release of cytokines has been identified as one of the key factors behind
poorer outcomes in COVID-19. This “cytokine storm” produces an excessive inflammatory …

Challenges and opportunities from targeting inflammatory responses to SARS-CoV-2 infection: a narrative review

V Lariccia, S Magi, T Serfilippi, M Toujani… - Journal of Clinical …, 2020 - mdpi.com
The novel coronavirus disease 2019 (COVID-19) is a global pandemic that continues to
sweep across the world, posing an urgent need for effective therapies and prevention of the …

[HTML][HTML] Immune response and potential therapeutic strategies for the SARS-CoV-2 associated with the COVID-19 pandemic

X Li, Y Zhang, L He, J Si, S Qiu, Y He… - … Journal of Biological …, 2022 - ncbi.nlm.nih.gov
Following onset of the first recorded case of Coronavirus disease 2019 (COVID-19) in
December 2019, more than 269 million cases and over 5.3 million deaths have been …

Targeting cytokine storm to manage patients with COVID-19: a mini-review

N Roshanravan, F Seif, A Ostadrahimi… - Archives of medical …, 2020 - Elsevier
Corona Virus Disease 2019 (COVID-19) pandemic is rapidly spreading all over the world.
Excessive immune responses trigger life-threatening cytokine release syndrome (CRS) …

[HTML][HTML] Human endeavor for anti-SARS-CoV-2 pharmacotherapy: a major strategy to fight the pandemic

R Wang, P Stephen, Y Tao, W Zhang, SX Lin - Biomedicine & …, 2021 - Elsevier
The global spread of COVID-19 constitutes the most dangerous pandemic to emerge during
the last one hundred years. About seventy-nine million infections and more than 1.7 million …

[HTML][HTML] Immune system response during viral Infections: Immunomodulators, cytokine storm (CS) and Immunotherapeutics in COVID-19

FH Pottoo, T Abu-Izneid, AM Ibrahim, MN Javed… - Saudi pharmaceutical …, 2021 - Elsevier
Coronaviruses are non-segmented and single stranded positive-sense RNA (+ ssRNA)
viruses. To date, 06 human coronaviruses (HCoVs) are reported; α-CoVs (HCoVs-NL63 and …

[HTML][HTML] SARS-Cov-2 infection: Response of human immune system and possible implications for the rapid test and treatment

G di Mauro, C Scavone, C Rafaniello, F Rossi… - International …, 2020 - Elsevier
The new coronavirus outbreak is an ongoing pandemic that is caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). The new coronavirus SARS-Cov-2 …

Understanding viral infection mechanisms and patient symptoms for the development of COVID-19 therapeutics

HM Choi, SY Moon, HI Yang, KS Kim - International Journal of Molecular …, 2021 - mdpi.com
Coronavirus disease 2019 (COVID-19), caused by the SARS-CoV-2 virus, has become a
worldwide pandemic. Symptoms range from mild fever to cough, fatigue, severe pneumonia …

A comprehensive review on potential therapeutics interventions for COVID-19

H Chugh, A Awasthi, Y Agarwal, RK Gaur… - European Journal of …, 2021 - Elsevier
COVID-19 is an infectious respiratory disease caused by SARS-CoV-2, a new beta
coronavirus that emerged in Wuhan, China. Being primarily a respiratory disease, it is highly …