New insights of emerging SARS-CoV-2: epidemiology, etiology, clinical features, clinical treatment, and prevention

G Guo, L Ye, K Pan, Y Chen, D Xing, K Yan… - Frontiers in cell and …, 2020 - frontiersin.org
Since the first reports that the novel coronavirus was showing human-to-human transmission
characteristics and asymptomatic cases, the number of patients with associated pneumonia …

Advances in pathogenesis, progression, potential targets and targeted therapeutic strategies in SARS-CoV-2-Induced COVID-19

H Zhou, WJ Ni, W Huang, Z Wang, M Cai… - Frontiers in …, 2022 - frontiersin.org
As the new year of 2020 approaches, an acute respiratory disease quietly caused by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), also known as coronavirus …

COVID-19: immunopathogenesis and Immunotherapeutics

L Yang, S Liu, J Liu, Z Zhang, X Wan… - Signal transduction and …, 2020 - nature.com
The recent novel coronavirus disease (COVID-19) outbreak, caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), is seeing a rapid increase in infected …

Global scenario, public health concerns and mitigation strategies to counter current ongoing SARS-CoV-2/COVID-19 pandemic

SB Barbuddhe, DB Rawool, PP Gaonkar… - Human Vaccines & …, 2020 - Taylor & Francis
Severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2), the etiological agent of
the novel coronavirus disease (COVID-19), has posed a great public health threat to the …

The signal pathways and treatment of cytokine storm in COVID-19

L Yang, X Xie, Z Tu, J Fu, D Xu, Y Zhou - Signal transduction and …, 2021 - nature.com
Abstract The Coronavirus Disease 2019 (COVID-19) pandemic has become a global crisis
and is more devastating than any other previous infectious disease. It has affected a …

An update to “novel therapeutic approaches for treatment of COVID-19”

N Hossein-Khannazer, B Shokoohian… - Journal of Molecular …, 2021 - Springer
Although the exact mechanism of pathogenesis in COVID-19 is not fully understood,
cytokine storm following viral infection plays an important role in the initiation and …

[HTML][HTML] Recent advances in management of COVID-19: A review

S Mouffak, Q Shubbar, E Saleh, R El-Awady - Biomedicine & …, 2021 - Elsevier
Abstract The coronavirus disease 2019 (COVID-19) pandemic caused and is still causing
significant mortality and economic consequences all over the globe. As of today, there are …

SARS-CoV-2/COVID-19: evolving reality, global response, knowledge gaps, and opportunities

MF Osuchowski, F Aletti, JM Cavaillon, SB Flohe… - Shock, 2020 - journals.lww.com
Approximately 3 billion people around the world have gone into some form of social
separation to mitigate the current severe acute respiratory syndrome coronavirus 2 (SARS …

Therapeutic targets and interventional strategies in COVID-19: mechanisms and clinical studies

YW Zhou, Y Xie, LS Tang, D Pu, YJ Zhu… - Signal transduction and …, 2021 - nature.com
Owing to the limitations of the present efforts on drug discovery against severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) and the lack of the understanding of the …

COVID-19: treating and managing severe cases

J Ai, Y Li, X Zhou, W Zhang - Cell research, 2020 - nature.com
The recent outbreak of COVID-19 caused by SARS-CoV-2 has led to a global pandemic, but
an international consensus on its treatment is still unavailable. In this highlight, we illustrate …