Our research elucidates the cleavage processes of the RNase III enzyme, DICER, which
plays a crucial role in the production of small RNAs, such as microRNAs (miRNAs) and …

RNase III Dicer produces small RNAs guiding sequence‐specific regulations, with important
biological roles in eukaryotes. Major Dicer‐dependent mechanisms are RNA interference …

Dicer has a central role in RNA-interference pathways by cleaving double-stranded RNAs
(dsRNAs) to produce small regulatory RNAs. Human Dicer can process long double …

MicroRNA (miRNA) and RNA interference (RNAi) pathways employ RNase III Dicer for the
biogenesis of small RNAs guiding post-transcriptional repression. Requirements for Dicer …

RNA silencing relies on specific and efficient processing of double-stranded RNA by Dicer,
which yields microRNAs (miRNAs) and small interfering RNAs (siRNAs),. However, our …

One of the most exciting recent developments in RNA biology has been the discovery of
small non-coding RNAs that affect gene expression through the RNA interference (RNAi) …

In humans, DICER is a key regulator of gene expression through its production of miRNAs
and siRNAs by processing miRNA precursors (pre-miRNAs), short-hairpin RNAs (shRNAs) …

The specialized ribonuclease Dicer plays a central role in eukaryotic gene expression by
producing small regulatory RNAs—microRNAs (miRNAs) and short interfering RNAs …

A hallmark of RNA silencing is a class of approximately 22-nucleotide RNAs that are
processed from double-stranded RNA precursors by Dicer. Accurate processing by Dicer is …

Dicer is a multi‐domain RNase III‐related endonuclease responsible for processing double‐
stranded RNA (dsRNA) to small interfering RNAs (siRNAs) during a process of RNA …