Designing redder and brighter fluorophores by synergistic tuning of ground and excited states

C Chen, MS Baranov, L Zhu, NS Baleeva… - Chemical …, 2019 - pubs.rsc.org
We strategically modified the GFP core via chemical synthesis to make redder and brighter
biomimetic fluorophores. Based on quantum calculations, solvatochromism analysis, and …

Developing Bright Green Fluorescent Protein (GFP)‐like Fluorogens for Live‐Cell Imaging with Nonpolar Protein− Chromophore Interactions

C Chen, SR Tachibana, NS Baleeva… - … A European Journal, 2021 - Wiley Online Library
Fluorescence‐activating proteins (FAPs) that bind a chromophore and activate its
fluorescence have gained popularity in bioimaging. The fluorescence‐activating and …

Self-restricted green fluorescent protein chromophore analogues: dramatic emission enhancement and remarkable solvatofluorochromism

H Deng, C Yu, L Gong, X Zhu - The Journal of Physical Chemistry …, 2016 - ACS Publications
The confinement effect of the β-barrel defines the emission profiles of the chromophores of
the green fluorescent protein (GFP) family. Here, we describe the design strategy and …

Devising efficient red‐shifting strategies for bioimaging: A generalizable donor‐acceptor fluorophore prototype

C Chen, C Fang - Chemistry–An Asian Journal, 2020 - Wiley Online Library
Long emission wavelengths, high fluorescence quantum yields (FQYs), and large Stokes
shifts are highly desirable features for fluorescent probes in biological imaging. However …

Green fluorescent protein inspired fluorophores

J Kong, Y Wang, W Qi, M Huang, R Su, Z He - Advances in Colloid and …, 2020 - Elsevier
Green fluorescence proteins (GFP) are appealing to a variety of biomedical and
biotechnology applications, such as protein fusion, subcellular localizations, cell …

Tuning Molecular Packing by Twisting Structure to Facilely Construct Highly Efficient Solid‐State Fluorophores for Two‐Photon Bioimaging and Photodynamic …

H Cao, Y Gao, B Wu, J Zhang, L Wang… - Advanced Functional …, 2024 - Wiley Online Library
The traditional design strategy for constructing highly bright solid‐state luminescent
materials relies on incorporating aggregation‐induced emission (AIE) scaffolds, molecular …

Engineering Near-Infrared Fluorescent Probes Based on Modulation of Molecular Excited States

C Yan, Z Zhu, Y Yao, Q Wang, Z Guo… - Accounts of Materials …, 2024 - ACS Publications
Conspectus Fluorescent dyes have revolutionized the way we study life science and
conduct medical diagnostics. Compared with visible wavelengths, near-infrared (NIR) …

meta-Fluorophores: an uncharted ocean of opportunities

T Chatterjee, M Mandal, S Mardanya… - Chemical …, 2023 - pubs.rsc.org
meta-Fluorophores (MFs) are unique ultra-light (in terms of molecular weight (MW))
fluorophores exhibiting luminescence with a wide colour gamut ranging from blue to the …

Acyl radical to rhodacycle addition and cyclization relay to access butterfly flavylium fluorophores

J Yin, Y Zhang, J Li, L Zhu, Y Lan, J You - Nature Communications, 2019 - nature.com
Transition metal-catalyzed C–H activation and radical reactions are two versatile strategies
to construct diverse organic skeletons. Here we show the construction of a class of flavylium …

Unlocking Multicolor Emissions in the Crystalline State through Dimerization and Configurational Transformation of a Single Fluorophore

Y Shao, R Huang, G Jiang, Q Shi, H Wei… - Chemistry of …, 2024 - ACS Publications
Multicolor luminescent materials with tunable properties hold great promise for a wide range
of applications in materials science. Unfortunately, the conventional approach to achieving …