Idiopathic pulmonary fibrosis: pathogenesis and therapeutic approaches

M Selman, VJ Thannickal, A Pardo, DA Zisman… - Drugs, 2004 - Springer
Idiopathic pulmonary fibrosis (IPF), also termed cryptogenic fibrosing alveolitis, is a
clinicopathological syndrome characterised by cough, exertional dyspneoa, basilar crackles …

Idiopathic pulmonary fibrosis: new insights in its pathogenesis

A Pardo, M Selman - The international journal of biochemistry & cell biology, 2002 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a unique type of chronic fibrosing lung disease of
unknown etiology. The sequence of the pathogenic mechanisms is unknown, but the …

[PDF][PDF] Idiopathic pulmonary fibrosis-a disorder of alveolar wound repair?

T Geiser - Swiss medical weekly, 2003 - smw.ch
Idiopathic pulmonary fibrosis (IPF) is a chronic and usually progressive lung disorder of
unknown aetiology. Conventional management of patients with IPF has been primarily …

[PDF][PDF] Beyond epithelial damage: vascular and endothelial contributions to idiopathic pulmonary fibrosis

J May, JA Mitchell, RG Jenkins - Journal of Clinical …, 2023 - Am Soc Clin Investig
Idiopathic pulmonary fibrosis (IPF) is a progressive scarring disease of the lung with poor
survival. The incidence and mortality of IPF are rising, but treatment remains limited …

The pathogenesis of idiopathic pulmonary fibrosis

WR Coward, G Saini, G Jenkins - Therapeutic advances in …, 2010 - journals.sagepub.com
Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic lung disease with an appalling
prognosis. The failure of anti-inflammatory therapies coupled with the observation that …

Idiopathic pulmonary fibrosis: from epithelial injury to biomarkers-insights from the bench side

M Kolb, K Borensztajn, B Crestani, M Kolb - Respiration, 2014 - karger.com
Idiopathic pulmonary fibrosis (IPF) is the most frequent fibrotic diffuse parenchymal lung
disease. Its prognosis is devastating:> 50% of the patients die within 3 years after diagnosis …

Unravelling the progressive pathophysiology of idiopathic pulmonary fibrosis

A Günther, M Korfei, P Mahavadi… - European …, 2012 - Eur Respiratory Soc
Idiopathic pulmonary fibrosis (IPF) is a life-threatening condition, with a median survival of<
3 yrs. The pathophysiology is not fully understood, but chronic injury of alveolar epithelial …

Pathogenetic pathways and novel pharmacotherapeutic targets in idiopathic pulmonary fibrosis

KM Antoniou, A Pataka, D Bouros… - Pulmonary pharmacology …, 2007 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a poorly understood disease that usually leads to death
within 5 years of diagnosis. Despite our better understanding of IPF pathogenesis, the …

Idiopathic pulmonary fibrosis

TJ Gross, GW Hunninghake - New England Journal of Medicine, 2001 - Mass Medical Soc
Idiopathic pulmonary fibrosis is characterized by radiographically evident interstitial
infiltrates predominantly affecting the lung bases and by progressive dyspnea and …

International consensus statement on idiopathic pulmonary fibrosis

U Costabel, TE King - European Respiratory Journal, 2001 - Eur Respiratory Soc
In the new millennium, idiopathic pulmonary fibrosis (IPF) is not what it was thought to be 20
years ago. In the past, the term was used for a heterogeneous group of interstitial lung …