Empirical performance of a self-controlled cohort method: lessons for developing a risk identification and analysis system
Background Observational healthcare data offer the potential to enable identification of risks
of medical products, but appropriate methodology has not yet been defined. The self …
of medical products, but appropriate methodology has not yet been defined. The self …
Empirical performance of a new user cohort method: lessons for developing a risk identification and analysis system
Background Observational healthcare data offer the potential to enable identification of risks
of medical products, but appropriate methodology has not yet been defined. The new user …
of medical products, but appropriate methodology has not yet been defined. The new user …
A comparison of the empirical performance of methods for a risk identification system
Background Observational healthcare data offer the potential to enable identification of risks
of medical products, and the medical literature is replete with analyses that aim to …
of medical products, and the medical literature is replete with analyses that aim to …
Empirical performance of the self-controlled case series design: lessons for developing a risk identification and analysis system
Background The self-controlled case series (SCCS) offers potential as an statistical method
for risk identification involving medical products from large-scale observational healthcare …
for risk identification involving medical products from large-scale observational healthcare …
Evaluating performance of risk identification methods through a large-scale simulation of observational data
PB Ryan, MJ Schuemie - Drug safety, 2013 - Springer
Background There has been only limited evaluation of statistical methods for identifying
safety risks of drug exposure in observational healthcare data. Simulations can support …
safety risks of drug exposure in observational healthcare data. Simulations can support …
Detecting adverse drug reactions following long-term exposure in longitudinal observational data: The exposure-adjusted self-controlled case series
Most approaches used in postmarketing drug safety monitoring, including spontaneous
reporting and statistical risk identification using electronic health care records, are primarily …
reporting and statistical risk identification using electronic health care records, are primarily …
Empirical performance of the case–control method: lessons for developing a risk identification and analysis system
Background Considerable attention now focuses on the use of large-scale observational
healthcare data for understanding drug safety. In this context, analysts utilize a variety of …
healthcare data for understanding drug safety. In this context, analysts utilize a variety of …
A comparison of estimators from self-controlled case series, case-crossover design, and sequence symmetry analysis for pharmacoepidemiological studies
Y Takeuchi, T Shinozaki, Y Matsuyama - BMC medical research …, 2018 - Springer
Background Despite the frequent use of self-controlled methods in
pharmacoepidemiological studies, the factors that may bias the estimates from these …
pharmacoepidemiological studies, the factors that may bias the estimates from these …
A simulation study to compare three self‐controlled case series approaches: correction for violation of assumption and evaluation of bias
W Hua, G Sun, CN Dodd, SA Romio… - … and drug safety, 2013 - Wiley Online Library
Purpose The assumption that the occurrence of outcome event must not alter subsequent
exposure probability is critical for preserving the validity of the self‐controlled case series …
exposure probability is critical for preserving the validity of the self‐controlled case series …
Multiple self-controlled case series for large-scale longitudinal observational databases
Characterization of relationships between time-varying drug exposures and adverse events
(AEs) related to health outcomes represents the primary objective in postmarketing drug …
(AEs) related to health outcomes represents the primary objective in postmarketing drug …