This chapter explores the politics of emerging debates about ethical and governance
challenges associated with genome editing, focusing in particular on applications of …

Genes are foundational to all organisms, yet their specific makeup is left to chance. Genome
editing technologies, such as CRISPR, allow scientists to manipulate the gene and rid it of …

The chapter provides an overview of the risk of misuse assessment and applies findings
from the assessment to determine how likely state and non-state actors are to use genome …

As the debate about heritable genome editing unfolds, divergent perspectives are coming
more clearly into view. Those who see it as offering little or no benefit while posing …

When scientists alter the genome of an organism, we typically reduce its ability to reproduce
in the wild. This limitation has prevented researchers from rendering wild insects unable to …

“Gene editing” describes a range of tools and techniques in molecular biology that permit
scientists to make directed changes to the genetic material of any living organism. Gene …

How to ensure the safe, effective, and ethical use of emerging biotechnologies, such as
clustered regularly interspaced short palindromic repeats (CRISPR)-based genome editing …

For more than 40 years, scientists have been developing tools and technologies for genome
modification; however, initial progress was slow and few outside of the molecular biology …

A, T, G, C: the alphabet code for the nucleotides that are the building blocks of life. Minor, but
consequential, changes in this DNA coding can change gene function. Researchers have …

Programmable nuclease-based genome editing technologies, including the clustered,
regularly interspaced, short palindromic repeats (CRISPR)/Cas9 system, are becoming an …