[HTML][HTML] Advancing how we learn from biodesign to mitigate risks with next-generation genome engineering

E AbrahamPaul, L LabbéJessy… - BioDesign …, 2020 - spj.science.org
In the last decade, the unprecedented simplicity and flexibility of the CRISPR-Cas system
has made it the dominant transformative tool in gene and genome editing. However, this …

CRISPR: A Futuristic Tool at the Intersection of Promise and Ethical Controversy in Biotechnology

A Mittal - Intersect: The Stanford Journal of Science, Technology …, 2024 - ojs.stanford.edu
This paper investigates CRISPR (Clustered Regularly Interspaced Short Palindromic
Repeats) technology, a tool that is revolutionary in the genetic engineering space. It has the …

A face-lift for biotech rules begins

M Shields - Nature Biotechnology, 2015 - nature.com
US federal agencies on October 30 held the first public meeting to comply with the White
House's order to modernize the federal regulatory system for genetically modified (GM) …

Governing Gene Editing in the European Union: Legal and Ethical Considerations

M Kritikos - Ethics and Integrity in Health and Life Sciences …, 2018 - emerald.com
The chapter analyses the re-emergence of gene editing as an object of policy attention at
the European Union (EU) level. Editing the genome of plants and/or animals has been a …

Governance of heritable human gene editing world-wide and beyond

Y Xue, L Shang - International Journal of Environmental Research and …, 2022 - mdpi.com
To date, the controversy surrounding the unknown risks and consequences of heritable
genome editing has grown, with such work raising biosafety and ethical concerns for future …

[引用][C] A crack in creation: The new power to control evolution

J Doudna, S Sternberg - 2017 - Random House

Governare il genoma: sapere e sovranità nei recenti sviluppi dell'ingegneria genetica

A Blasimme - Notizie di Politeia, 2017 - politeia-centrostudi.org
This paper provides an overview of the positions that emerged from the international debate
concerning the governance of genome editing (CRISPR/Cas9). The paper also offers …

Making space for CRISPR: scientists' translation work to make gene editing a legitimate technology

M Svingen, L Jahren - Science and Public Policy, 2024 - academic.oup.com
This paper focuses on scientists working with CRISPR in Norway, where genetic
modification is thought to be a particularly stigmatized technology with strict regulation and a …

Regulatory Silos: Assessing the United States' Regulation of Biotechnology in the Age of Gene Drives

C Dooley - Geo. Envtl. L. Rev., 2017 - HeinOnline
The advent of CRISPR gene editing technology has moved the use of gene drives,
genetically engineering an organism to push a preferred gene through a target population …

Engineering values into genetic engineering: a proposed analytic framework for scientific social responsibility

PL Sankar, MK Cho - The American journal of bioethics, 2015 - Taylor & Francis
Recent experiments have been used to “edit” genomes of various plant, animal and other
species, including humans, with unprecedented precision. Furthermore, editing the Cas9 …