Both skin and oral mucosa are characterized by the presence of keratinized epithelium in
direct apposition to an underlying collagen-dense connective tissue. Despite significant …

Epidermal tissue repair represents a complex series of temporal and dynamic events
resulting in wound closure. Matricellular proteins, not normally expressed in quiescent adult …

The matricellular protein periostin is expressed in the skin. Although periostin has been
hypothesized to contribute to dermal homeostasis and repair, this has not been directly …

Cutaneous wound repair is a highly ordered and well‐coordinated process involving various
cell lineages and many molecular effectors. Cell–matrix interactions through integrin …

The matricellular protein periostin is strongly expressed in collagen‐rich connective tissues
such as periodontal ligaments (PDLs), skeletal muscle, adipose tissue, tendons, skin, and …

Integrity of the extracellular matrix (ECM) is essential for maintaining the normal structure
and function of connective tissues. ECM is secreted locally by cells and organized into a …

Differentiation of fibroblasts to myofibroblasts and collagen fibrillogenesis are two processes
essential for normal cutaneous development and repair, but their misregulation also …

Although the matricellular protein periostin is prominently upregulated in skin and gingival
healing, it plays contrasting roles in myofibroblast differentiation and matrix synthesis …

More than 10 years have passed since the naming of periostin derived from its expression
sites in the periosteum and periodontal ligament. Following this finding, we have …

During tissue healing, the dynamic and temporal alterations required for effective repair
occur in the structure and composition of the extracellular matrix (ECM). Matricellular …