Acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection continues to be a
worldwide public health crisis. Among the several severe manifestations of this disease …

Recent evidence proposed that the severity of Coronavirus disease 2019 (COVID-19)
patients is a consequence of cytokine storm, characterized by increased IL-1β, IL-6, IL-18 …

Cytokine signaling, especially interferon (IFN) signaling is closely linked to several aspects
of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection. During initial …

Recent advances in the pathophysiologic understanding of the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) infection has indicated that patients with severe …

Background In inflamed tissue, immune cells are accumulated, and various intercellular
signals are involved in the pathogenesis. Janus kinases (JAKs) are typical tyrosine kinases …

Evolving information has identified disease mechanisms and dysregulation of host biology
that might be targeted therapeutically in coronavirus disease 2019 (COVID-19). Thrombosis …

As the incidence of COVID-19 increases with time, more and more efforts are made to pave
a way out for the therapeutic strategies to deal with the disease progression. Inflammation …

COVID-19 patients have a high incidence of thrombosis, and thromboembolic complications
are associated with severe COVID-19 and high mortality. COVID-19 disease is associated …

Abstract Coronavirus disease 2019 (COVID-19), which is caused by severe acute
respiratory syndrome coronavirus-2 (SARS-CoV-2), is associated with a high mortality rate …

Abstract Coronavirus disease 2019 (COVID-19) has spread rapidly throughout the world.
The range of the disease is broad but among hospitalized patients with COVID-19 are …