H3. 3 is a highly conserved nonreplicative histone variant. H3. 3 is enriched in promoters
and enhancers of active genes, but it is also found within suppressed heterochromatin …

H3. 3 is a histone variant that marks transcription start sites as well as telomeres and
heterochromatic sites on the genome. The presence of H3. 3 is thought to positively …

Histone H3. 3 is a highly conserved histone H3 replacement variant in metazoans and has
been implicated in many important biological processes, including cell differentiation and …

Canonical histone H3 and histone variant H3. 3 are posttranslationally modified with the
genomic distribution of these marks denoting different features and these modifications may …

Background The histone variant H3. 3 plays key roles in regulating chromatin states and
transcription. However, the role of endogenous H3. 3 in mammalian cells and during …

Histone variant H3. 3 plays novel roles in development as compared to canonical H3
proteins and is the most commonly mutated histone protein of any kind in human disease …

During metazoan development, the marked change in developmental potential from the
parental germline to the embryo raises an important question regarding how the next life …

Within the nucleus, the interplay between lineage-specific transcription factors and
chromatin dynamics defines cellular identity. Control of this interplay is necessary to properly …

Background The histone variant H3. 3 plays a critical role in maintaining the pluripotency of
embryonic stem cells (ESCs) by regulating gene expression programs important for lineage …

Abstract Human histone H1. 5, in mice called H1b, belongs to the family of linker histones
(H1), which are key players in chromatin organization. These proteins sit on top of …