Electrophilic Cyclization of 2-(1-Alkynyl)-2-alken-1-ones Using the I2/K3PO4 System:  An Efficient Synthesis of Highly Substituted Iodofurans

Y Liu, S Zhou - Organic Letters, 2005 - ACS Publications
The electrophilic cyclization of 2-(1-alkynyl)-2-alken-1-ones in the presence of various
alcohols or carbon-based nucleophiles offers an efficient and straightforward route to highly …

A Novel Iodine‐Promoted Tandem Cyclization: An Efficient Synthesis of Substituted 3, 4‐Diiodoheterocyclic Compounds

KG Ji, HT Zhu, F Yang, XZ Shu, SC Zhao… - … A European Journal, 2010 - Wiley Online Library
Five-and six-membered heterocyclic rings occur as key structural subunits in numerous
natural products, such as polyacetylenic esters,[1] phytane-type diterpenedilactones,[2] …

ICl-Induced Intramolecular Electrophilic Cyclization of 1-[4′-Methoxy (1, 1′-biphenyl) 2-yl] alkynones-A Facile Approach to Spiroconjugated Molecules.

Y Chen, X Liu, M Lee, C Huang… - … A European Journal, 2013 - search.ebscohost.com
Spiro compounds: An iodine monochloride‐induced intramolecular cyclization of 1‐[4′‐
methoxy (1, 1′‐biphenyl) 2‐yl] alkynones has been developed (see scheme). An …

Selective Synthesis of Spiro[4,5]trienyl Acetates via an Intramolecular Electrophilic ipso-Iodocyclization Process

BX Tang, DJ Tang, S Tang, QF Yu, YH Zhang… - Organic …, 2008 - ACS Publications
A general and efficient intramolecular electrophilic ipso-iodocyclization of para-unactivated
arylalkynes has been developed for the synthesis of spiro [4, 5] trienyl acetates. In the …

Recent advances in the synthesis of iodoheterocycles via iodocyclization of functionalized alkynes

B Gabriele, R Mancuso… - Current Organic Chemistry, 2014 - ingentaconnect.com
Iodocyclization reactions are acquiring an increasing importance in organic synthesis, in
view of the possibility to obtain iodine-containing heterocycles starting from readily available …

Iodine-mediated synthesis of heterocycles via electrophilic cyclization of alkynes

T Aggarwal, S Kumar, AK Verma - Organic & biomolecular chemistry, 2016 - pubs.rsc.org
Iodine has been recognized as an efficient, non-toxic, readily available and easy-to-handle
electrophilic reagent to favour halocyclization reactions for the synthesis of novel …

Facile synthesis of halogenated spiroketals via a tandem iodocyclization

J Wang, HT Zhu, YX Li, LJ Wang, YF Qiu, ZH Qiu… - Organic …, 2014 - ACS Publications
A strategy for the synthesis of spiroketal compounds through a tandem iodocyclization of 1-
(2-ethynylphenyl)-4-hydroxybut-2-yn-1-one derivatives is presented. This reaction could …

Alkylation/Ipso-cyclization of Active Alkynes Leading to 3-Alkylated Aza-and Oxa-spiro [4, 5]-trienones

P Chen, JH Fan, WQ Yu, BQ Xiong, Y Liu… - The Journal of …, 2022 - ACS Publications
A method for the preparation of 3-alkylated spiro [4.5] trienones via alkylation/ipso-
cyclization of activated alkynes with 4-alkyl-DHPs under transition-metal-free conditions is …

An efficient synthesis of highly substituted furans via the electrophilic cyclization of 1-(1-alkynyl)-cyclopropyl ketones

X Huang, W Fu, M Miao - Tetrahedron Letters, 2008 - Elsevier
An efficient synthesis of highly substituted furans via the electrophilic cyclization of 1-(1-alkynyl)-cyclopropyl
ketones - ScienceDirect Skip to main contentSkip to article Elsevier logo Journals & Books …

Intramolecular ipso-Halocyclization of 4-(p-Unsubstituted-aryl)-1-alkynes Leading to Spiro[4,5]trienones: Scope, Application, and Mechanistic Investigations

BX Tang, YH Zhang, RJ Song, DJ Tang… - The Journal of …, 2012 - ACS Publications
A new, general method for the synthesis of spiro [4, 5] trienones is described by the
intramolecular ipso-halocyclization of 4-(p-unsubstituted-aryl)-1-alkynes. In the presence of …