… These TGF-β-mediated modulations lead to inflammation and lung injury in COVID-19
and impaired coagulation. Therefore, targeting TGF-β and its signaling is a potential …

… (eg chronic lung disease and cardiac remodelling in the lung … ways to target the RAS pathway
in COVID-19, an idea that … clinical trials for COVID-19 that target the RAS pathway. These …

… -CoV-2 infection and cardiac disease. The Notch signalling is a … of COVID-19- associated
heart and lungs disease. … family that processes protein of the secretory pathway, is a type 1 …

… construction, … lung damage, resulting from an increased pulmonary vascular permeability,
leading to intersticial edema, and eventually endotheliitis, activation of coagulation pathways …

… lung histopathological characteristics of COVID-19, not only for diagnostic purpose but also
to evaluate changes that can reflect pathophysiological pathways that … of acute lung injury. …

… that lung injury from β-coronavirus infection results from an aberrant host response activating
multiple AT2 UPR stress pathways… (and even fibrotic) lung remodeling in mice and humans. …

… proportional to the viral load and lung damage observed [6]. … the pathological vascular
remodeling and the cardiovascular … These molecules modulate the same signaling pathways that …

… ; however, pulmonary remodeling with honeycomb change was … with coronavirus disease
2019 (COVID-19) lung disease … development of lung fibrosis via cytokine pathways. Antifibrotic …

… by the SARS-CoV-2 (COVID-19) pandemic. Even if a patient survives the ALI, resultant …
pathologic findings of ALI, focusing on the stages of injury and pathways to repair or fibrosis. …

… who developed fibrotic remodeling following COVID-19 lung injury compared with those who
… identify multiple pathways that are altered during fibrotic remodeling following COVID-19, …