C Marchesi, P Paradis, EL Schiffrin - Trends in pharmacological sciences, 2008 - cell.com
… The renin–angiotensin system (RAS) plays a key role in the development and … injury involves a low-grade inflammatoryprocess and that inflammation plays a significant role in the …
AR Brasier, A Recinos III, MS Eledrisi - … , thrombosis, and vascular …, 2002 - Am Heart Assoc
… process. Our recent studies have defined a molecular mechanism for a biological positive-feedback loop that explains how vascular inflammation … atherosclerotic vascular inflammation. …
F Montecucco, A Pende, F Mach - Mediators of inflammation, 2009 - Wiley Online Library
… Another important issue is the mechanism of action of the different classes of renin-angiotensin blockers. If angiotensin II is the key player in the inflammatoryprocesses in …
E Cantero-Navarro, B Fernandez-Fernandez… - Molecular and cellular …, 2021 - Elsevier
… Angiotensin type 2 receptor (AT2R) activation can oppose AT1R actions, such as … inflammation has not been conclusively proven. Angiotensin-converting enzyme 2 (ACE2) can process …
S Sciarretta, F Paneni, F Palano, D Chin… - Clinical …, 2009 - portlandpress.com
… , the RAAS (renin–angiotensin–… inflammation through the activation of different cell types and the secretion of cytokines and chemokines. RAAS-induced myocardial inflammation leads …
… In the process, inflammatory factors produced by the immune system and RAS intimately interplay and synergistically promote elevation of blood pressure and the development of RAS-…
… inflammatoryprocess, an increase in life span and a reduction in the severity of some autoimmune processes [… most important modulators of inflammatory diseases and the physiological …
… A typical example of how inflammation underlies the development of cardiovascular … the inflammatory cytokines. Endothelium dysfunction due to injury by the inflammatoryprocess has …
M Ruiz-Ortega, V Esteban, J Egido - Trends in cardiovascular medicine, 2007 - Elsevier
… reninangiotensin system (RAS) participates in the pathogenesis of cardiovascular diseases. Although angiotensin … of N-terminal angiotensin degradation product, angiotensin IV (AngIV)…