Exosome therapeutics for COVID‐19 and respiratory viruses

KD Popowski, PUC Dinh, A George, H Lutz, K Cheng - View, 2021 - Wiley Online Library
… of various viruses including the novel severe acute respiratory syndrome coronavirus 2. …
exosomes and respiratory viruses, describe potential exosome therapeutics for viral infections, …

Potential therapeutic application of mesenchymal stem cell-derived exosomes in SARS-CoV-2 pneumonia

A Akbari, J Rezaie - Stem cell research & therapy, 2020 - Springer
… 2 virus characterized by a severe acute respiratory impairment … such as exosomes (MSC-Exo)
considerably improved lungtherapeutic application of exosomes in SARS-CoV-2 virus

Multifunctional role of exosomes in viral diseases: From transmission to diagnosis and therapy

P Chaudhari, V Ghate, M Nampoothiri, S Lewis - Cellular signalling, 2022 - Elsevier
… of exosomes in chronic lung allograft rejection in patients suffering from respiratory viral
infections from 17 viruses, … and increased lung SAgs were detected in isolated exosomes from …

Exosomes: Applications in respiratory infectious diseases and prospects for coronavirus disease 2019 (COVID-19)

J Feng, A Waqas, Z Zhu, L Chen - Journal of Biomedical …, 2020 - ingentaconnect.com
… the use of exosomes in various respiratory infectious diseases … new ideas for the treatment
of new coronavirus infections. … that exosomes may have a therapeutic effect on COVID-19. …

Diverse effects of exosomes on COVID-19: a perspective of progress from transmission to therapeutic developments

S Gurunathan, MH Kang, JH Kim - Frontiers in Immunology, 2021 - frontiersin.org
Exosomes derived from respiratory syncytial virus–infected cells were able to activate an
innate immune response by inducing cytokine and chemokine release from human monocytes …

Mesenchymal stem cells and exosome therapy for COVID-19: current status and future perspective

A Gupta, S Kashte, M Gupta, HC Rodriguez… - Human cell, 2020 - Springer
… These effects have paved the way towards the therapeutic use of this novel … acute lung
disorders, MSC-derived exosomes were also found to be responsible for direct inhibition of viral

Therapeutic role of mesenchymal stem cell-derived exosomes in respiratory disease

MJ Zargar, S Kaviani, M Vasei… - … Research & Therapy, 2022 - Springer
… , which showed that MSC exosomes could be a potent therapeutic candidate for treating …
is equivalent to many viruses and results in complications such as ARDS and lung damage, …

Exosome-mediated small RNA delivery: a novel therapeutic approach for inflammatory lung responses

D Zhang, H Lee, X Wang, A Rai, M Groot, Y Jin - Molecular Therapy, 2018 - cell.com
… system targeting lung macrophages using serum-derived EXOs. We also demonstrated
an effective approach to treating inflammatory lung responses using therapeutic siRNAs or …

Therapeutic potential of mesenchymal stem cells and their exosomes in severe novel coronavirus disease 2019 (COVID-19) cases

A Tsuchiya, S Takeuchi, T Iwasawa, M Kumagai… - Inflammation and …, 2020 - Springer
… acute lung injury (ALI) induced by the influenza A (H5N1) virus… UC-MSC exosomes have
some therapeutic effects and only … MSCs at the early stage of H7N9 infection, while the other six …

Respiratory syncytial virus infection changes cargo composition of exosome released from airway epithelial cells

HS Chahar, T Corsello, AS Kudlicki, N Komaravelli… - Scientific reports, 2018 - nature.com
respiratory tract infections in children. In this study, we characterized exosomes released from
RSV-infected lung … to develop new therapeutic approaches. In this study, we characterized …