Lipopolysaccharide mediates hepatic stellate cell activation by regulating autophagy and retinoic acid signaling

M Chen, J Liu, W Yang, W Ling - Autophagy, 2017 - Taylor & Francis
… that LPS induces autophagy in macrophages, linking 2 ancient processes, autophagy and
innate … that the LPS regulates HSC activation through autophagy and retinoic acid signaling. …

Retinoic acid alleviates cisplatin-induced acute kidney injury through activation of autophagy

J Wu, C Zheng, X Wan, M Shi, K McMillan… - Frontiers in …, 2020 - frontiersin.org
… This study demonstrated that RA activated autophagy and inhibited apoptosis after
cisplatin-induced injury, as shown by reduced cleaved-caspase-3 by immunoblotting and less …

Chemical modulation of chaperone-mediated autophagy by retinoic acid derivatives

J Anguiano, TP Garner, M Mahalingam, BC Das… - Nature chemical …, 2013 - nature.com
… Chaperone-mediated autophagy (CMA… retinoic acid receptor α (RARα) inhibits CMA and
apply structure-based chemical design to develop synthetic derivatives of all-trans-retinoic acid

Retinoic acid-induced IgG production in TLR-activated human primary B cells involves ULK1-mediated autophagy

AB Eriksen, ML Torgersen, KL Holm, G Abrahamsen… - Autophagy, 2015 - Taylor & Francis
… of autophagy in retinoic acid (RA)-induced differentiation of toll-like receptor (TLR)-stimulated
human B cells into Ig-secreting cells. Thus, RA enhanced autophagy in … of the autophagy-…

[HTML][HTML] Induction of autophagy is a key component of all-trans-retinoic acid-induced differentiation in leukemia cells and a potential target for pharmacologic …

N Orfali, TR O'Donovan, MJ Nyhan, A Britschgi… - Experimental …, 2015 - Elsevier
Autophagy is a conserved protein degradation pathway with important roles in … autophagy
in APL cell differentiation. We found that autophagy is increased during all-trans-retinoic acid (…

[HTML][HTML] Retinoic acid receptor α promotes autophagy to alleviate liver ischemia and reperfusion injury

C Zhong, LY Pu, MM Fang, Z Gu, JH Rao… - World Journal of …, 2015 - ncbi.nlm.nih.gov
… of autophagy and the relationship between all-trans retinoic acid (ATRA) and autophagy
in … liver IR injury by inducing autophagy and it may involves retinoic acid receptor α (RARα) …

[HTML][HTML] All-trans-retinoic acid inhibits the malignant behaviors of hepatocarcinoma cells by regulating autophagy

S Fang, C Hu, L Xu, J Cui, L Tao, M Gong… - American Journal of …, 2020 - ncbi.nlm.nih.gov
… -retinoic acid (ATRA) can inhibit the malignant behaviors of hepatocarcinoma cells. Autophagy
… Our study demonstrated that ATRA induces autophagy and autophagic cell death via the …

Targeting retinoic acid receptor alpha-corepressor interaction activates chaperone-mediated autophagy and protects against retinal degeneration

R Gomez-Sintes, Q Xin, JI Jimenez-Loygorri… - Nature …, 2022 - nature.com
… also effective in activating CMA, have a negative impact on other types of autophagy such
as … molecules that selectively activate CMA without affecting other forms of autophagy 11 . …

All-trans Retinoic Acid Augments Autophagy during Intracellular Bacterial Infection

MM Coleman, SA Basdeo, AM Coleman… - American journal of …, 2018 - atsjournals.org
retinoic acid (… autophagy resulting in a reduced bacterial burden in human macrophages
infected with Mtb and Bordetella pertussis, but not bacillus Calmette-Guérin (BCG). Autophagy

Retinoic acid worsens ATG10-dependent autophagy impairment in TBK1-mutant hiPSC-derived motoneurons through SQSTM1/p62 accumulation

A Catanese, F Olde Heuvel, M Mulaw, M Demestre… - Autophagy, 2019 - Taylor & Francis
… We then verified if the mismatch between 4HPR-activated autophagy and intrinsic autophagic
bottlenecks might be a general feature of multiple ALS-related molecular defects. To this …