[PDF][PDF] An update on cytokine storm in covid-19 infection: Pivotal to the survival of the patients

EI Obeagu, S Hamisi, UO Bunu - Int. J. Adv. Res. Biol. Sci, 2023 - researchgate.net
… of immune cells,lymphocyte and macrophages which produce immense amount of cytokine
which result into cytokine storm. Cytokine storm is cause by the colossal release of … cytokines

Targeting cytokine storm to manage patients with COVID-19: a mini-review

N Roshanravan, F Seif, A Ostadrahimi… - Archives of medical …, 2020 - Elsevier
… this review, we addressed the inflammatory pathways of SARS-CoV-2 and its relationship with
the host cytokine storm. … The understanding of molecular mechanisms involved in this viral …

[HTML][HTML] Harnessing the immune system to overcome cytokine storm and reduce viral load in COVID-19: a review of the phases of illness and therapeutic agents

S Khadke, N Ahmed, N Ahmed, R Ratts, S Raju… - Virology journal, 2020 - Springer
… We describe the phases of COVID-19 infection, discuss immune dysregulation resulting
in cytokine storm, and review immunomodulatory options being studied in this disease. …

The role of IL-6 and other mediators in the cytokine storm associated with SARS-CoV-2 infection

A Copaescu, O Smibert, A Gibson, EJ Phillips… - Journal of Allergy and …, 2020 - Elsevier
… in its severest form has been marked by elevation of IL-6, IL-10, TNF-α, and other cytokines
… This review highlights our current state of knowledge of immune mechanisms and targeted …

[HTML][HTML] Molecular mechanisms of Ebola virus pathogenesis: focus on cell death

L Falasca, C Agrati, N Petrosillo, A Di Caro… - Cell Death & …, 2015 - nature.com
… by a cytokine storm, with secretion of numerous pro-inflammatory cytokines, which induces
a … In this review, we analyze the molecular mechanisms at the basis of Ebola pathogenesis …

[HTML][HTML] A new investigation into the molecular mechanism of andrographolide towards reducing cytokine storm

A Alzahrani - Molecules, 2022 - mdpi.com
… be exploited as therapeutics to reduce cytokine storm, the drug development … cytokines
that are secreted as a result of cytokine storm. We used molecular docking analyses, molecular

The looming storm: blood and cytokines in COVID-19

S Kaur, R Bansal, S Kollimuttathuillam, AM Gowda… - Blood reviews, 2021 - Elsevier
cytokine storm, hypercoagulable state and some rare presentations of this disease hence
becomes imperative. Through this review, we aim … cytokine storm in patients with SARS-CoV-2. …

[HTML][HTML] SARS-CoV-2 causes a different cytokine response compared to other cytokine storm-causing respiratory viruses in severely ill patients

M Olbei, I Hautefort, D Modos, A Treveil… - Frontiers in …, 2021 - frontiersin.org
… Hyper-induction of pro-inflammatory cytokines, also known as a cytokine storm or
cytokine release syndrome (CRS), is one of the key aspects of the currently ongoing SARS-CoV-2 …

[HTML][HTML] Interplay between interleukin-6 signaling and the vascular endothelium in cytokine storms

S Kang, T Kishimoto - Experimental & molecular medicine, 2021 - nature.com
… types of cytokine storms. In this review, we present the current understanding of the diverse
roles of IL-6, its receptors, and its signaling during acute severe systemic inflammation. …

[HTML][HTML] Natural products for treating cytokine storm–related diseases: Therapeutic effects and mechanisms

M Liu, Q Wang, W Xu, J Wu, X Xu, H Yang… - Biomedicine & …, 2023 - Elsevier
… Initially reviews the potential natural products for the treatment of cytokine storm. … Cytokine
storm (CS) is primarily observed in cases of sepsis and infectious diseases, where it is …