Natural killer cell evasion is essential for infection by rhesus cytomegalovirus

ER Sturgill, D Malouli, SG Hansen, BJ Burwitz… - PLoS …, 2016 - journals.plos.org
… transduced with Ad148 were co-incubated with human NK cells when compared to control
[35] consistent with our conclusion that HCMV UL148 is not an NK cell evasion factor despite …

Evasion of CD8+ T Cells Is Critical for Superinfection by Cytomegalovirus

SG Hansen, CJ Powers, R Richards, AB Ventura… - Science, 2010 - science.org
… ) can superinfect persistently infected hosts despite CMV-specific humoral and cellular
of rhesus CMV–infected rhesus macaques (RM) requires evasion of CD8 + T cell immunity by …

Immune evasion by human cytomegalovirus: lessons in immunology and cell biology

WAM Loenen, CA Bruggeman, E Wiertz - Seminars in immunology, 2001 - Elsevier
… strategies to treat and prevent HCMV-associated diseases. HCMV, as well as its counterparts
in other mammalians, such as the murine, rat and rhesus CMV, have acquired homologs of …

Identification and functional characterization of a novel Fc gamma-binding glycoprotein in rhesus cytomegalovirus

P Kolb, S Sijmons, MR McArdle, H Taher… - Journal of …, 2019 - Am Soc Microbiol
… By gene mapping and with the help of a novel cell-based reporter assay system we …
antagonist of rhesus FcγR activation. We further demonstrate that, unlike evasion of T cell immunity, …

Cross-species rhesus cytomegalovirus infection of cynomolgus macaques

BJ Burwitz, D Malouli, BN Bimber, JS Reed… - PLoS …, 2016 - journals.plos.org
… The RhCMV 68-1/gag, RhCMV 68-1/env, and RhCMV 68–1.2/gag vectors as well as all
viruses carrying deletions in the US6 family of T cell evasion genes used in our T cell activation …

Multifaceted evasion of the interferon response by cytomegalovirus

EE Marshall, AP Geballe - Journal of Interferon & Cytokine …, 2009 - liebertpub.com
… success of HCMV depends in part on its ability to evade host … Rhesus CMV (RhCMV) also
represses the very early ISG response but by a mechanism that differs from that used by HCMV

Rhesus monkeys for a nonhuman primate model of cytomegalovirus infections

HL Itell, A Kaur, JD Deere, PA Barry… - Current opinion in virology, 2017 - Elsevier
… of the cellular interleukin-10 signaling pathway and avoidance of natural killer cell activation,
via preventing NKG2D ligand surface expression, contributes to RhCMV and HCMV viral …

Comparison of vaccination with rhesus CMV (RhCMV) soluble gB with a RhCMV replication-defective virus deleted for MHC class I immune evasion genes in a …

S Valencia, RB Gill, KC Dowdell, Y Wang, R Hornung… - Vaccine, 2019 - Elsevier
… single cycle rhesus CMV (RhCMV) deleted for glycoprotein L (gL) and the MHC class I
immune evasion genes Rh178 and Rh182-189, and restored its epithelial cell tropism by …

Rhesus Cytomegalovirus-encoded Fcγ-binding glycoproteins facilitate viral evasion from IgG-mediated humoral immunity

CE Otero, S Petkova, M Ebermann, H Taher, N John… - bioRxiv, 2024 - biorxiv.org
… humans, we identified and characterized vFcγRs encoded by rhesus CMV (RhCMV). We 49
… Upon transfection of 293T cells, we measured rhesus IgG1 binding via flow cytometry 141 …

Human cytomegalovirus immunity and immune evasion

SE Jackson, GM Mason, MR Wills - Virus research, 2011 - Elsevier
… to HCMV with a number … CMV (CCMV) is very closely related to HCMV this is not a widely
applicable model primate system. However, rhesus macaques and the associated rhesus CMV