… suggestions that the NME1/7-2 RNA may play a role in rRNA processing (5, 25, 31). The
results we report here indicate that RNase MRP is indeed involved in rRNA processing. …

… Our results demonstrate that RNase MRP accurately cleaves pre-rRNA at site A3 in vitro. …
of RNase MRP mutants, we conclude that RNase MRP is directly implicated in rRNA processing…

… RNase MRP is predominantly localized in the nucleolus, where it is responsible for precursor
ribosomal RNA (pre-rRNA) … 1 (ITS1) to release the mature 5.8S rRNA (9–12). S. cerevisiae …

… during processing of rRNA precursors. RNase MRP is evolutionary related to RNase P which
is … The ribonucleoprotein complex MRP is an endonuclease processing ribosomal RNA …

… RNase MRP is a ubiquitously expressed eukaryotic endoribonuclease that cleaves various
RNAs, including ribosomal… aspects of RNase MRP, discuss the targeting of RNase MRP in …

… for the RNA component of the respective RNase MRP en… RNase MRP enzymatic activity
and the identity of the RNase … of RNase MRP is in late-stage processing of rRNA and that a …

… RNase MRP has three known substrates in yeast; mitochondrial RNA (mtRNA), precursor
ribosomal RNA (pre-rRNA… the pre-rRNA substrate of the RNase MRP holoenzyme and showed …

… We noticed that the ITS1 regions (the substrate for the MRP enzyme) of hemiascomycetes
precursor rRNA are highly conserved (Supplemental Fig. S2). Thus, the sequence …

… RNase MRP and/or RNase P in ribosomal RNA processing in human cells. Ribosomal RNA
processing was studied by metabolic labeling and northern blot hybridisation of total RNA …

… RNase MRP cleaves at a specific site in the precursor-rRNA transcript to initiate processing
of the 5.8S rRNA… and P3) between RNase MRP RNA and RNase P RNA of S. cerevisiae. The …