… too early to make firm conclusions about specific risk genes underlying most GWAS loci. As
… to point toward specific risk genes and pathways. Table 1 Genetic loci associated with BD. …

… conditions share common genetic risk factors with bipolar disorder, others … genes for bipolar
disorder that have emerged so far. As no gene could be considered as an undeniable risk …

… evidence for a major genetic contribution to risk. There are … lifetime risk of bipolar disorder in
relatives of a bipolar proband are… the implications of genetic investigation of bipolar disorder. …

… Gene-wide analyses of genome-wide association data sets: evidence for multiple common
risk alleles for schizophrenia and bipolar disorder and for overlap in genetic risk. Mol …

… These studies estimated the heritability (proportion of disorder risk in the population
attributable to genetic variation) of BPD to be 79%–93%, substantially higher than even medical …

… , including schizophrenia and bipolar disorder. Here we investigate whether genes
involved in oxidative stress regulation are associated with increased risk for bipolar disorder. …

… between genetic risk for bipolar disorder and ADHD, compared to genetic risk for BD and …
more loosely related to DSM-IV criteria for bipolar II disorder. It is possible that the DAWBA is a …

… of bipolar disorder, along with putative demographic, genetic and … gene–environment
interactions, as well as the mechanisms by which risk factors interact to lead to bipolar disorder. …

… and essential genes with a strong … risk genes in humans, Caenorhabditis elegans, zebrafish,
and Drosophila. Furthermore, we examined gene-gene interactions among the risk genes …

… studies (GWAS) on bipolar disorder (BPD) suggested novel risk genes. However, only few
of them were followed up and further, the specificity of these genes is even more elusive. To …