… -scale sequencing study aimed at increasing the number of genes … We performed whole-exome
sequencing of 2869 ALS … ALS genes were found to be associated, and TBK1 (the gene …

… To identify new risk genes, we performed exome sequencing in a large cohort from the …
We then carried out rare deleterious variant identification followed by case-control gene-based …

… parallel exome sequencing of 237 channel genes in … genes is prevalent in both groups at
similar complexity, revealing that even deleterious ion channel mutations confer uncertain risk …

… We report the exome sequencing and genotyping results of 1379 individuals in 457
families with at least one offspring affected with ASD, including 418 simplex and 39 multiplex …

… BC risk variants, and this manuscript reviews 12 familial BC whole-exome sequencing efforts.
… a modest number of novel BC risk genes were identified, and 90% and 97% of the exome-…

… research and whether and how this information differs from standard information about
the risks and benefits of genetic research. In many cases, the answers are complex and …

… exome sequencing studies to date, we identify genes in which disruptive coding variants confer
substantial risk for schizophrenia at exome-… a decade of sequence data, harmonization of …

… exome sequence data generation We combined BD case–control whole-exome sequencing
… However, this is the first time that exome sequencing and joint analysis has been performed …

… , exome sequencing makes identification of genetic mutations and risk factors possible in
families and samples that were deemed insufficiently informative for previous genetic studies. …

… sequencing, it is now possible to assess this hypothesis at the scale of all 20,000 human genes
by whole-exome sequencing (… collapsed at the gene-level or even gene networks. These …