… cancer risk in our analysis; 13 of the remaining genes had an … or high risk according to our
analysis), and the other 3 genes (… An association between breast cancer risk and variants in …

… The majority of credible risk single-nucleotide … target genes in breast cells at each locus,
we demonstrate a strong overlap between candidate target genes and somatic driver genes in …

… gene-set analysis, we evaluated whether genes with predicted miR-137 target sites were
enriched for smaller association … in a far larger set of genes with predicted miR-137 target sites (…

… Our results strongly suggest that TLR7 and TLR8 are novel risk genes in asthma and related
atopic disorders. Several non-genetic lines of evidence support the involvement of these …

… We used all 19,427 protein-coding genes from the NCBI 37.3 gene definitions as the basis
… We annotated all SNPs in our association analysis to these genes, resulting in 18,355 genes …

… exposures, genetic analysis has the potential to define which risk factors are indeed …
association studies (GWAS) have collectively reported a total of 31 loci, associated with CAD risk at …

… SNPs, we performed a permutation analysis with 5000 iterations. For each iteration, the
phenotypes were permuted and the association analysis was conducted as described above. …

… polymorphism-based association analysis and were not previously reported. We found that
53 … power of gene-based association analysis in detecting disease-susceptibility genes. Our …

… Furthermore, the effect of these loci on CAD risk in a broader range of individuals remains to
… association analysis of single nucleotide polymorphisms at each locus with CAD risk in 11 …

… factors contribute to the variation of bone mineral density (BMD), which is a major risk factor
of … robust gene-based association analysis, focusing on identifying “novel” genes for BMD. …