[PDF][PDF] Clinical efficacy of lopinavir/ritonavir in the treatment of Coronavirus disease 2019.

XT Ye, YL Luo, SC Xia, QF Sun, JG Ding… - European Review for …, 2020 - europeanreview.org
… The main purpose of this study was to evaluate the clinical effect of LPV/r combined with the
routine adjuvant therapeutic drugs on patients with COVID-19. As revealed, the time of body …

A review of the preclinical and clinical efficacy of remdesivir, hydroxychloroquine, and lopinavir-ritonavir treatments against COVID-19

D Maciorowski, SZE Idrissi, Y Gupta… - … the Science of Drug …, 2020 - journals.sagepub.com
… vitro animal models and clinical studies of drugs … lopinavir-ritonavir combinations. These
compounds have been frequently touted as top candidates to treat COVID-19, but recent clinical

Combination therapy containing ritonavir plus saquinavir has superior short-term antiretroviral efficacy: a randomized trial

O Kirk, TL Katzenstein, J Gerstoft, L Mathiesen… - Aids, 1999 - journals.lww.com
… plus ritonavir in combination with two nucleoside analogues is generally safe, and has
superior short-term antiviral efficacy compared with indinavir and ritonavir also combined with two …

Clinical efficacy of nirmatrelvir and ritonavir combination for treating diabetic patients with COVID‐19

JY Wu, MY Liu, TH Liu, MH Chuang… - Journal of Medical …, 2023 - Wiley Online Library
… The aim of this study was to investigate the clinical efficacy of a combination of nirmatrelvir
and ritonavir (NMV-r) for treating COVID-19 in patients with diabetes mellitus (DM). This …

Safety and efficacy of ritonavir and saquinavir in combination with zidovudine and lamivudine

C Michelet, E Bellissant, A Ruffault… - Clinical …, 1999 - Wiley Online Library
… We conclude that ritonavir and saquinavir in combination are well tolerated and induce a
high and sustained antiretroviral efficacy in protease inhibitor–naive patients with CD4 cell …

[PDF][PDF] Clinical efficacy and safety of lopinavir/ritonavir combined with other antiviral in the treatment of coronavirus disease 2019 (COVID-19)

YU Airong, FAN Xing, Z Yan, Z Fan, Z Linlin… - Herald of …, 2020 - yydbzz.com
… Conclusion Lopinavir/ ritonavir combined with … CT imagesꎬbut the effects on clinical symptoms
are not obviousꎬand … the safety of lopinavir/ ritonavir in clinical application. KEY WORDS …

Lopinavir/ritonavir in the treatment of HIV-1 infection: a review

A Chandwani, J Shuter - Therapeutics and clinical risk …, 2008 - Taylor & Francis
… the pharmacologic and clinical aspects of lopinavir/ritonavir in the … Coformulated
lopinavir/ritonavir was the first combination pill … clinical efficacy with no clinical resistance to …

Safety and efficacy of lopinavir/ritonavir combination in COVID-19: A systematic review, meta-analysis, and meta-regression analysis

A Bhattacharyya, S Kumar, P Sarma… - Indian journal of …, 2020 - journals.lww.com
… against SARS-CoV-2 activity invitro, clinical efficacy is not established. In this meta-analysis, …
efficacy and safety of this combination and rationale of using this combination in COVID-19. …

Discovery of ritonavir, a potent inhibitor of HIV protease with high oral bioavailability and clinical efficacy

DJ Kempf, HL Sham, KC Marsh… - Journal of medicinal …, 1998 - ACS Publications
… -defining clinical events 32 and has recently been licensed by the Food and Drug Administration
for the therapy of HIV infection. Ongoing clinical studies using ritonavir in combination

Once-daily atazanavir/ritonavir versus twice-daily lopinavir/ritonavir, each in combination with tenofovir and emtricitabine, for management of antiretroviral-naive HIV-1 …

JM Molina, J Andrade-Villanueva, J Echevarria… - The Lancet, 2008 - thelancet.com
clinical efficacy of once-daily atazanavir/ritonavir and twice-daily lopinavir/ritonavir, both given
in combination … Here, we report the 48-week primary efficacy and safety results of this study…