… such as obesity, infertility and cancer [22]. In this review, we summarize the function and
therapeutic advances of m 6 A modifications in human cancer and provide their promising …

… the RNA methylation landscape in human cancer cells. The reversible RNA methylation, …
the rate of translation, regulates essential features of cancer cells. In glioblastoma, METTL3 or …

… In conclusion, the integrity of m 6 A RNAs methylation modification is maintained by writers,
erasers and readers (Fig. 1). Its dynamic balance enables the body to maintain normal …

… the RNA methyltransferase DNMT2. We found that DNMT2 is variably expressed in human
cancer … a role of DNMT2 in the site-specific methylation of tRNA Asp in human cancer cells. …

… and that shifts in the DNA methylation patterns in their regulatory regions contribute to …
human cancer. However, much remains to be discovered about how their disruption affect cancer …

… drugs targeting DNA methylation is becoming a hot zone in cancer therapy research.
However, there exist less RNA methylation activity in cancer cells as the methylation in RNA often …

… RNA methylation has emerged as a fundamental process in … that RNA methylation is
essential for many biological functions, and its dysregulation is associated with human cancer …

… and loss of gene function in cancer 10 . Hence, we investigated whether RNA-dependent
DNA methylation might operate in human cancers to mediate epigenetic silencing using the …

… Bioinformatics analysis showed that m6A RNA methylation regulators can contribute to the
malignant progression of BCA [133]. Gu et al demonstrated that METTL14 inhibited the self-…

… data generated by Illumina HumanMethylation450K BeadChip and 12 567 mRNA/microRNA
expression data generated by RNA-seq/ miRNA-seq in 18 human cancers. Table 1 …